ONM-6: APOPTOSIS AND THE QUALITY DECREASE OF SPERM PARAMETERS IN INFERTILE MEN.—META ANALYSIS

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FATHI NAJAFI T.; SABAGHIAN E.; HEJAZI M.; ASNA ASHARI F.; YADEGARI Z.; HAJIBABA KASHANI S.

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Paper Information

Journal: International Journal of Fertility & Sterility Year:2010 | Volume:4 | Issue:SUPPLEMENT 1 (5TH ROYAN NURSING AND MIDWIFERY SYMPOSIUM) Page(s): 86-87

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Title

ONM-6: APOPTOSIS AND THE QUALITY DECREASE OF SPERM PARAMETERS IN INFERTILE MEN.—META ANALYSIS

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Keywords

APOPTOSIS

SPERM QUALITY

INFERTILITY

Abstract

Background: The main objectives of this study are to examine the Meta analysis of the relation between APOPTOSIS and decline of sperm motility, concentration and semen volume in infertile men. Through testis biopsy, high amounts of APOPTOSIS have been reported. Since the results of sperm analysis shows a medium prediction of fertility. INFERTILITY due to male factor is 30%-40% of INFERTILITY of couples, so clinical evaluations and new methods in male factor can be a more accurate prediction for the condition and function of their sperm, therefore sperm APOPTOSIS can be a useful index for evaluating male fertility.Materials and Methods: An internet study, by the use of Medline and Scopus database from 2003 to 2009 was performed. The key words were sperm APOPTOSIS and its quality. This study is done on human subjects. The selected articles were not biased nor had the minimum bias. Among the 20 initial articles, only 9 had the wanted characteristics and were chosen. The results were obtained from a Random-Effects model which is more conservative than a fixed-Effect model. The homogeneousness of the effects was performed by the use of Cochran’s Chi-squared (Q-Test) and I2 statistics. The homogeneousness of the effects depends on the type of variables which evaluate the APOPTOSIS and quality of sperms. The effects of small study and low quality of the study were done through cumulative Meta analysis and analysis of sub groups. Metaregration was done for recognizing the Covariance of the study level and its Heterogenic. The bias of study was done through Funnel plot. CMA statistical software is used in this Meta analysis. Results: This results show a significant difference between motility of sperm in two groups.(p=0.000)also based on Random model the concentration of sperm in control and case groups are significant differences. (p=0.001) but there is not a significant deference between semen volume and intensity of APOPTOSIS (p=0.275). Conclusion: APOPTOSIS and its intensity can affect the motility and concentration of sperm therefore can be affect sperm parameters.

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APA: Copy

FATHI NAJAFI, T., SABAGHIAN, E., HEJAZI, M., ASNA ASHARI, F., YADEGARI, Z., & HAJIBABA KASHANI, S.. (2010). O_NM-6: APOPTOSIS AND THE QUALITY DECREASE OF SPERM PARAMETERS IN INFERTILE MEN.—META ANALYSIS. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 4(SUPPLEMENT 1 (5TH ROYAN NURSING AND MIDWIFERY SYMPOSIUM)), 86-87. SID. https://sid.ir/paper/304681/en

Vancouver: Copy

FATHI NAJAFI T., SABAGHIAN E., HEJAZI M., ASNA ASHARI F., YADEGARI Z., HAJIBABA KASHANI S.. O_NM-6: APOPTOSIS AND THE QUALITY DECREASE OF SPERM PARAMETERS IN INFERTILE MEN.—META ANALYSIS. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2010;4(SUPPLEMENT 1 (5TH ROYAN NURSING AND MIDWIFERY SYMPOSIUM)):86-87. Available from: https://sid.ir/paper/304681/en

IEEE: Copy

T. FATHI NAJAFI, E. SABAGHIAN, M. HEJAZI, F. ASNA ASHARI, Z. YADEGARI, and S. HAJIBABA KASHANI, “O_NM-6: APOPTOSIS AND THE QUALITY DECREASE OF SPERM PARAMETERS IN INFERTILE MEN.—META ANALYSIS,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 4, no. SUPPLEMENT 1 (5TH ROYAN NURSING AND MIDWIFERY SYMPOSIUM), pp. 86–87, 2010, [Online]. Available: https://sid.ir/paper/304681/en

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