PATHOGENESIS AND CAUSES OF PREMATURE OVARIAN FAILURE: AN UPDATE

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EBRAHIMI MAHBOD; AKBARI ASBAGH FIROOZEH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

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Journal: International Journal of Fertility & Sterility Year:2011 | Volume:5 | Issue:2 Page(s): 54-65

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Information Journal Paper

Title

PATHOGENESIS AND CAUSES OF PREMATURE OVARIAN FAILURE: AN UPDATE

Author(s)

EBRAHIMI MAHBOD | AKBARI ASBAGH FIROOZEH | Issue Writer Certificate

Keywords

PREMATURE MENOPAUSE

PREMATURE OVARIAN FAILURE

HYPERGONADOTROPIC OVARIAN FAILURE

HYPERGONADOTROPIC HYPOGONADISM

PREMATURE OVARIAN INSUFFICIENCY

Abstract

Premature ovarian failure (POF) affects 1% of young women. This condition has significant psychological sequelae and major health implications. POF seriously interferes with fertility and family planning. Diverse etiologies are associated with POF.Literature review related to the causes and pathogenesis of POF, cited between the year 1900 and May 2010.POF may be either spontaneous or induced. The known causes include:-Genetic disorders, which could involve the X chromosome or autosomes. However, the growing body of literature demonstrates a list of newly discovered mutations that may be responsible for causing POF. Most of these mutations are extremely rare, and most cases of POF are still considered to be idiopathic.-Autoimmune causes; there is some evidence of an association of POF with lymphocytic oophoritis and other autoimmune disorders. Antiovarian antibodies are reported in POF, but their specificity and pathogenic role are obscure.-Iatrogenic causes; chemotherapy, radiotherapy and pelvic surgery can lead to POF.-Infectious Causes; some viral and microbial infections can be followed by POF.-Environmental toxins, such as cigarette smoking are reported as risk factors of spontaneous POF.-Idiopathic; in most cases, no identifiable etiology can be recognized after complete evaluation.

Cites

CASE REPORT: A DE NOVO RECIPROCAL X; 9 TRANSLOCATION IN A PATIENT WITH PREMATURE OVARIAN FAILURE

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APA: Copy

EBRAHIMI, MAHBOD, & AKBARI ASBAGH, FIROOZEH. (2011). PATHOGENESIS AND CAUSES OF PREMATURE OVARIAN FAILURE: AN UPDATE. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 5(2), 54-65. SID. https://sid.ir/paper/304960/en

Vancouver: Copy

EBRAHIMI MAHBOD, AKBARI ASBAGH FIROOZEH. PATHOGENESIS AND CAUSES OF PREMATURE OVARIAN FAILURE: AN UPDATE. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2011;5(2):54-65. Available from: https://sid.ir/paper/304960/en

IEEE: Copy

MAHBOD EBRAHIMI, and FIROOZEH AKBARI ASBAGH, “PATHOGENESIS AND CAUSES OF PREMATURE OVARIAN FAILURE: AN UPDATE,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 5, no. 2, pp. 54–65, 2011, [Online]. Available: https://sid.ir/paper/304960/en

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