SERUM AND PERITONEAL FLUID LEVELS OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN WOMEN WITH ENDOMETRIOSIS

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KIANPOUR MARYAM; NEMATBAKHSH MEHDI; AHMADI SAYED MEHDI; JAFARZADEH MEHRANGIZ; HAJJARIAN MASOMEH; PEZESHKI ZAHRA; SAFARI TAHEREH; ESHRAGHI JAZI FATEMEH

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Journal: International Journal of Fertility & Sterility Year:2013 | Volume:7 | Issue:2 Page(s): 96-99

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Title

SERUM AND PERITONEAL FLUID LEVELS OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN WOMEN WITH ENDOMETRIOSIS

Author(s)

Keywords

ENDOMETRIOSIS

VASCULAR ENDOTHELIAL GROWTH FACTOR

PERITONEAL FLUID

Abstract

Background: ENDOMETRIOSIS is known as one of the most common disease in women of reproductive age. Due to important role of VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) in neo-vascularization for the implantation of endometrial cell, and also presence of different studies reported VEGF level in the serum and PERITONEAL FLUID (PF) in ENDOMETRIOSIS patients, this study was designed to determine the serum and PF levels of VEGF in ENDOMETRIOSIS patients, and to compare with normal subjects.Materials and Methods: In this descriptive study, 179 women subjected to laparoscopy for the evaluation of infertility or pelvic pain were allocated into the following two groups: group I: different types of ENDOMETRIOSIS patients (n=90) and group II: non-ENDOMETRIOSIS patients (n=89). The PF from pelvis and venous blood samples were obtained. The VEGF concentration of the serum and PF were measured using enzyme immunoassay kit and were compared using t test.Results: The level of VEGF in serum was significantly less than that in PF in both groups (p=0.00). However, ENDOMETRIOSIS patients had significantly higher level of VEGF in PERITONEAL FLUID than non-ENDOMETRIOSIS patients (p=0.043).Conclusion: According to our findings, ENDOMETRIOSIS is not associated with change in the level of circulating VEGF.

Cites

METHODOLOGICAL CONCERNS REGARDING LEVELS OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) IN SERUM OF WOMEN WITH ENDOMETRIOSIS (LETTER TO THE EDITOR)

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APA: Copy

KIANPOUR, MARYAM, NEMATBAKHSH, MEHDI, AHMADI, SAYED MEHDI, JAFARZADEH, MEHRANGIZ, HAJJARIAN, MASOMEH, PEZESHKI, ZAHRA, SAFARI, TAHEREH, & ESHRAGHI JAZI, FATEMEH. (2013). SERUM AND PERITONEAL FLUID LEVELS OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN WOMEN WITH ENDOMETRIOSIS. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 7(2), 96-99. SID. https://sid.ir/paper/305409/en

Vancouver: Copy

KIANPOUR MARYAM, NEMATBAKHSH MEHDI, AHMADI SAYED MEHDI, JAFARZADEH MEHRANGIZ, HAJJARIAN MASOMEH, PEZESHKI ZAHRA, SAFARI TAHEREH, ESHRAGHI JAZI FATEMEH. SERUM AND PERITONEAL FLUID LEVELS OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN WOMEN WITH ENDOMETRIOSIS. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2013;7(2):96-99. Available from: https://sid.ir/paper/305409/en

IEEE: Copy

MARYAM KIANPOUR, MEHDI NEMATBAKHSH, SAYED MEHDI AHMADI, MEHRANGIZ JAFARZADEH, MASOMEH HAJJARIAN, ZAHRA PEZESHKI, TAHEREH SAFARI, and FATEMEH ESHRAGHI JAZI, “SERUM AND PERITONEAL FLUID LEVELS OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN WOMEN WITH ENDOMETRIOSIS,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 7, no. 2, pp. 96–99, 2013, [Online]. Available: https://sid.ir/paper/305409/en

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