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Information Journal Paper

Title

THE EFFECTS OF PROGESTERONE ON OOCYTE MATURATION AND EMBRYO DEVELOPMENT

Pages

  74-81

Abstract

 Oocyte maturation and EMBRYO development are controlled by intra-ovarian factors suchas steroid hormones. PROGESTERONE (P4) exists in the follicular fluid that contributes to normal mammalian ovarian function and has several critical functions during EMBRYO development and implantation, including endometrial receptivity, EMBRYOnic survival during gestation and transformation of the endometrial stromal cells to decidual cells.It is well known that the physiological effects of P4 during the pre-implantation stages of some mammal’s EMBRYOs are mediated by P4 receptors and their gene expression is determined. The effects of P4 on OOCYTEs and EMBRYO development have been assessed bysome investigations, with contradictory results. P4, a dominant steroid in follicular fluid at approximately 18 hours after the luteinizing hormone (LH) surge may have a critical role in maturation of OOCYTEs at the germinal stage. However, it has been shown that different concentrations of P4 could not improve IN VITRO MATURATION rates of germinal vesicles (GV) in cumulus OOCYTE complexes (COCs) and cumulus denuded OOCYTEs (CDOs). Culture media supplemented with P4 significantly improved mouse EMBRYO development. In addition, an in vivo experimental design has shown high blastocyst survival and implantation rates in P4-treated mice.In this review we explain some of the findings that pertain to the effects of P4 on OOCYTE maturation and EMBRYO development bothin vitro and in vivo.

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    Cite

    APA: Copy

    SALEHNIA, MOJDEH, & ZAVAREH, SAEID. (2013). THE EFFECTS OF PROGESTERONE ON OOCYTE MATURATION AND EMBRYO DEVELOPMENT. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 7(2), 74-81. SID. https://sid.ir/paper/305412/en

    Vancouver: Copy

    SALEHNIA MOJDEH, ZAVAREH SAEID. THE EFFECTS OF PROGESTERONE ON OOCYTE MATURATION AND EMBRYO DEVELOPMENT. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2013;7(2):74-81. Available from: https://sid.ir/paper/305412/en

    IEEE: Copy

    MOJDEH SALEHNIA, and SAEID ZAVAREH, “THE EFFECTS OF PROGESTERONE ON OOCYTE MATURATION AND EMBRYO DEVELOPMENT,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 7, no. 2, pp. 74–81, 2013, [Online]. Available: https://sid.ir/paper/305412/en

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