مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

COMPARISON OF RISK OF PRETERM LABOR BETWEEN VAGINAL PROGESTERONE AND17-ALPHA-HYDROXY-PROGESTERONE CAPROATE IN WOMEN WITH THREATENED ABORTION: A RANDOMIZED CLINICAL TRIAL

Pages

  162-168

Abstract

 Background: Threatened miscarriage is a common complication in pregnancy that leads to adverse pregnancy outcomes such as preterm labor. This study aimed to compare the vaginal PROGESTERONE (Cyclogest) versus 17-alpha-hydroxyPROGESTERONE caproate (Proluton) on preventing preterm labor in pregnant women with THREATENED ABORTION at less than 34 weeks’ gestational age.Materials and Methods: This balanced randomized, double-blind, single-center controlled clinical trial included 190 women with THREATENED ABORTION. They were then randomly allocated into Cyclogest (n=95) and 17-alpha-hydroxyPROGESTERONE caproate (Proluton, n=95) groups. Interested outcome was preterm labor less than 34 weeks. The Pearson chi-square and Student’s t test were used to compare two groups. The data were analyzed by Stata software version 13.Results: The risks of preterm labor less than 34 weeks in Proluton and Cyclogest groups were 8.6 and 6.52%, respectively. There was no significant difference for risk of preterm labor less than 34 weeks [relative ratio (RR): 1.31, 95% confidence interval (CI): 0.47- 3.66, P=0.59] between two groups.Conclusion: Risk of preterm labor in the vaginal PROGESTERONE group and 17-alpha-hydroxyPROGESTERONE caproate group in pregnant women with THREATENED ABORTION is the same (Registration Number: IRCT2014123120504N1).

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    Cite

    APA: Copy

    BEIGI, ABOOTALEB, ESMAILZADEH, AREZOO, & PIRJANI, REYHANE. (2016). COMPARISON OF RISK OF PRETERM LABOR BETWEEN VAGINAL PROGESTERONE AND17-ALPHA-HYDROXY-PROGESTERONE CAPROATE IN WOMEN WITH THREATENED ABORTION: A RANDOMIZED CLINICAL TRIAL. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 10(2), 162-168. SID. https://sid.ir/paper/305877/en

    Vancouver: Copy

    BEIGI ABOOTALEB, ESMAILZADEH AREZOO, PIRJANI REYHANE. COMPARISON OF RISK OF PRETERM LABOR BETWEEN VAGINAL PROGESTERONE AND17-ALPHA-HYDROXY-PROGESTERONE CAPROATE IN WOMEN WITH THREATENED ABORTION: A RANDOMIZED CLINICAL TRIAL. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2016;10(2):162-168. Available from: https://sid.ir/paper/305877/en

    IEEE: Copy

    ABOOTALEB BEIGI, AREZOO ESMAILZADEH, and REYHANE PIRJANI, “COMPARISON OF RISK OF PRETERM LABOR BETWEEN VAGINAL PROGESTERONE AND17-ALPHA-HYDROXY-PROGESTERONE CAPROATE IN WOMEN WITH THREATENED ABORTION: A RANDOMIZED CLINICAL TRIAL,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 10, no. 2, pp. 162–168, 2016, [Online]. Available: https://sid.ir/paper/305877/en

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