FOLLICLE STIMULATING HORMONE AND ANTI-MULLERIAN HORMONE AMONG FERTILE AND INFERTILE WOMEN IN ILE-IFE, NIGERIA: IS THERE A DIFFERENCE?

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OKUNOLA TEMITOPE; OLUSEGUN AJENIFUJA KAYODE; MOREBISE LOTO OLABISI; SALAWU AFOLABI; OLUSEYI OMITINDE STEPHEN

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Journal: International Journal of Fertility & Sterility Year:2017 | Volume:11 | Issue:1 Page(s): 33-39

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Title

FOLLICLE STIMULATING HORMONE AND ANTI-MULLERIAN HORMONE AMONG FERTILE AND INFERTILE WOMEN IN ILE-IFE, NIGERIA: IS THERE A DIFFERENCE?

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Keywords

INFERTILITY

OVARIAN RESERVE

FOLLICLE STIMULATING HORMONE

ANTI-MULLERIAN HORMONE

Abstract

Background: Reduced OVARIAN RESERVE predicts poor ovarian response and poor success rates in infertile women who undergo assisted reproductive technology (ART). OVARIAN RESERVE also decreases with age but the rate of decline varies from one woman to another. This study aims to detect differences in OVARIAN RESERVE as measured by basal serum FOLLICLE STIMULATING HORMONE (FSH) and ANTI-MULLERIAN HORMONE (AMH) between a matched cohort of fertile and infertile regularly menstruating women, 18-45 years of age.Materials and Methods: This case-control study involved 64 fertile and 64 subfertile women matched by age at recruitment. Peripheral blood samples were taken from the women recruited from the Gynecological and Outpatient Clinics of Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria. Serum FSH and AMH were quantified using ELISA at the Metabolic Research Laboratory of LAUTECH Teaching Hospital, Ogbomoso, Nigeria.Results: A significant difference existed in the mean FSH of fertile (6.97±3.34) and infertile (13.34±5.24, P=0.013) women. We observed a significant difference in AMH between fertile (2.71±1.91) and infertile (1.60±2.51, P=0.029) women. There was a negative correlation between FSH and AMH in both fertile (r=-0.311, P=0.01) and infertile (r=-0.374, P=0.002) women.Conclusion: The difference in OVARIAN RESERVE observed in this study suggests that reduced OVARIAN RESERVE in regularly menstruating women may be associated with early ovarian ageing or subfertility.

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APA: Copy

OKUNOLA, TEMITOPE, OLUSEGUN AJENIFUJA, KAYODE, MOREBISE LOTO, OLABISI, SALAWU, AFOLABI, & OLUSEYI OMITINDE, STEPHEN. (2017). FOLLICLE STIMULATING HORMONE AND ANTI-MULLERIAN HORMONE AMONG FERTILE AND INFERTILE WOMEN IN ILE-IFE, NIGERIA: IS THERE A DIFFERENCE?. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 11(1), 33-39. SID. https://sid.ir/paper/305918/en

Vancouver: Copy

OKUNOLA TEMITOPE, OLUSEGUN AJENIFUJA KAYODE, MOREBISE LOTO OLABISI, SALAWU AFOLABI, OLUSEYI OMITINDE STEPHEN. FOLLICLE STIMULATING HORMONE AND ANTI-MULLERIAN HORMONE AMONG FERTILE AND INFERTILE WOMEN IN ILE-IFE, NIGERIA: IS THERE A DIFFERENCE?. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2017;11(1):33-39. Available from: https://sid.ir/paper/305918/en

IEEE: Copy

TEMITOPE OKUNOLA, KAYODE OLUSEGUN AJENIFUJA, OLABISI MOREBISE LOTO, AFOLABI SALAWU, and STEPHEN OLUSEYI OMITINDE, “FOLLICLE STIMULATING HORMONE AND ANTI-MULLERIAN HORMONE AMONG FERTILE AND INFERTILE WOMEN IN ILE-IFE, NIGERIA: IS THERE A DIFFERENCE?,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 11, no. 1, pp. 33–39, 2017, [Online]. Available: https://sid.ir/paper/305918/en

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