ACCURACY OF TWO-DIMENSIONAL TRANSVAGINAL SONOGRAPHY AND OFFICE HYSTEROSCOPY FOR DETECTION OF UTERINE ABNORMALITIES IN PATIENTS WITH REPEATED IMPLANTATION FAILURES OR RECURRENT PREGNANCY LOSS

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SHIVA MARZIEH; AHMADI FIROUZEH; ARABIPOOR AREZOO; OROMIEHCHI MANSOUREH; CHEHRAZI MOHAMMAD

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Journal Paper

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Journal: International Journal of Fertility & Sterility Year:2018 | Volume:11 | Issue:4 Page(s): 287-292

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Title

ACCURACY OF TWO-DIMENSIONAL TRANSVAGINAL SONOGRAPHY AND OFFICE HYSTEROSCOPY FOR DETECTION OF UTERINE ABNORMALITIES IN PATIENTS WITH REPEATED IMPLANTATION FAILURES OR RECURRENT PREGNANCY LOSS

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Keywords

DIAGNOSIS

HYSTEROSCOPY

ULTRASONOGRAPHY

UTERINE

Abstract

Background: We sought to compare diagnostic values of two-dimensional transvaginal sonography (2D TVS) and office HYSTEROSCOPY (OH) for evaluation of endometrial pathologies in cases with repeated implantation failure (RIF) or recurrent pregnancy loss (RPL).Materials and Methods: This prospective study was performed at Royan Institute from December 2013 to January 2015. TVS was performed before HYSTEROSCOPY as part of the routine diagnostic work-up in 789 patients with RIF or RPL. UTERINE biopsy was performed in cases with abnormal DIAGNOSIS in TVS and/or HYSTEROSCOPY. We compared the diagnostic accuracy values of TVS in detection of UTERINE abnormalities with OH by receiver operating characteristic (ROC) curve analysis.Results: TVS examination detected 545 (69%) normal cases and 244 (31%) pathologic cases, which included 84 (10.6%) endometrial polyps, 15 (1.6%) UTERINE fibroids, 10 (1.3%) Asherman’s syndrome, 9 (1.1%) endometrial hypertrophy, and 126 (15.9%) septate and arcuate uterus. TVS and OH concurred in 163 pathologic cases, although TVS did not detect some pathology cases (n=120). OH had 94% sensitivity, 95% specificity, 62% positive predictive value (PPV), and 99% negative predictive value (NPV) for detection of endometrial polyps. In the DIAGNOSIS of myoma, sensitivity, specificity, PPV, and NPV were 100%. TVS had a sensitivity of 50% and specificity of 98% for the DIAGNOSIS of myoma. For polyps, TVS had a sensitivity of 54% and specificity of 80%. Area under the ROC curve (AUROC) was 70.69% for the accuracy of TVS compared to OH.Conclusion: TVS had high specificity and low sensitivity for detection of UTERINE pathologies in patients with RIF or RPL compared with OH. OH should be considered as a workup method prior to treatment in patients with normal TVS findings.

Cites

Assessment of Transvaginal Ultrasonography Accuracy in the Diagnosis of Uterine Pathologies in Women with Abnormal Uterine Bleeding

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APA: Copy

SHIVA, MARZIEH, AHMADI, FIROUZEH, ARABIPOOR, AREZOO, OROMIEHCHI, MANSOUREH, & CHEHRAZI, MOHAMMAD. (2018). ACCURACY OF TWO-DIMENSIONAL TRANSVAGINAL SONOGRAPHY AND OFFICE HYSTEROSCOPY FOR DETECTION OF UTERINE ABNORMALITIES IN PATIENTS WITH REPEATED IMPLANTATION FAILURES OR RECURRENT PREGNANCY LOSS. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 11(4), 287-292. SID. https://sid.ir/paper/305953/en

Vancouver: Copy

SHIVA MARZIEH, AHMADI FIROUZEH, ARABIPOOR AREZOO, OROMIEHCHI MANSOUREH, CHEHRAZI MOHAMMAD. ACCURACY OF TWO-DIMENSIONAL TRANSVAGINAL SONOGRAPHY AND OFFICE HYSTEROSCOPY FOR DETECTION OF UTERINE ABNORMALITIES IN PATIENTS WITH REPEATED IMPLANTATION FAILURES OR RECURRENT PREGNANCY LOSS. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2018;11(4):287-292. Available from: https://sid.ir/paper/305953/en

IEEE: Copy

MARZIEH SHIVA, FIROUZEH AHMADI, AREZOO ARABIPOOR, MANSOUREH OROMIEHCHI, and MOHAMMAD CHEHRAZI, “ACCURACY OF TWO-DIMENSIONAL TRANSVAGINAL SONOGRAPHY AND OFFICE HYSTEROSCOPY FOR DETECTION OF UTERINE ABNORMALITIES IN PATIENTS WITH REPEATED IMPLANTATION FAILURES OR RECURRENT PREGNANCY LOSS,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 11, no. 4, pp. 287–292, 2018, [Online]. Available: https://sid.ir/paper/305953/en

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