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Information Journal Paper

Title

Cumulative Live-Birth Rates by Maternal Age after One or Multiple In Vitro Fertilization Cycles: An Institutional Experience

Pages

  34-40

Abstract

 Background: The aim of this retrospective study is to investigate the cumulative live birth rate (CLBR) following one or more completed in vitro fertilization (IVF) cycles (up to 6 cycles) stratified by Maternal Age and type of infertility. Materials and Methods: In this retrospective study, five hundred forty-seven women who received 736 fresh ovarian stimulation/embryo transfer cycles between January 2016 and December 2016 were included in the study at a tertiary care center located in Lebanon. Results: In all women, the live birth rate for the first cycle was 33. 0% [95% confidence interval (CI): 27. 8-38. 2]. The CLBR showed an increase with each successive fresh cycle to reach 56. 9% (95% CI: 51. 2-62. 4) after 3 cycles and 67. 9% (95% CI: of 62. 5-73. 0) after 6 cycles. The CLBR following 6 cycles reached 69. 9% (95% CI: 63. 8-75. 6) in women younger than 35 years. In women older than 40 years, however, the live birth rate for the first cycle was significantly low at 3. 1% (95% CI: 0. 3-9. 5) with a plateau in success rates after 4 cycles reaching 21. 9% (95% CI: 9. 2-40. 0). Couples with different types of infertility had CLBRs ranging from 65% to 72%, with the exception of women with low ovarian reserve, where CLBRs reached 29. 4% (95% CI: 10. 3-56. 0). Conclusion: The CLBR at a referral center in a Middle Eastern country reached 67. 9 % after 6 cycles, with variations by age and type of infertility treatment. These findings are encouraging for patients insisting to extend their treatment beyond 4 to 5 cycles.

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    APA: Copy

    Khalife, Dalia, Nassar, Anwar, Khalil, Ali, Awwad, Johnny, Musa, Antoine Abu, Hannoun, Antoine, Taha, Lina El, Khalifeh, Fatin, Abiad, May, & Ghazeeri, Ghina. (2020). Cumulative Live-Birth Rates by Maternal Age after One or Multiple In Vitro Fertilization Cycles: An Institutional Experience. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 14(1), 34-40. SID. https://sid.ir/paper/306080/en

    Vancouver: Copy

    Khalife Dalia, Nassar Anwar, Khalil Ali, Awwad Johnny, Musa Antoine Abu, Hannoun Antoine, Taha Lina El, Khalifeh Fatin, Abiad May, Ghazeeri Ghina. Cumulative Live-Birth Rates by Maternal Age after One or Multiple In Vitro Fertilization Cycles: An Institutional Experience. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2020;14(1):34-40. Available from: https://sid.ir/paper/306080/en

    IEEE: Copy

    Dalia Khalife, Anwar Nassar, Ali Khalil, Johnny Awwad, Antoine Abu Musa, Antoine Hannoun, Lina El Taha, Fatin Khalifeh, May Abiad, and Ghina Ghazeeri, “Cumulative Live-Birth Rates by Maternal Age after One or Multiple In Vitro Fertilization Cycles: An Institutional Experience,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 14, no. 1, pp. 34–40, 2020, [Online]. Available: https://sid.ir/paper/306080/en

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