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Information Journal Paper

Title

The Effect of Lycopene Supplementation on Mood Status and Quality of Life in Infertile Men: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Author(s)

 NOURI MEHRAN | NASR ESFAHANI MOHAMMAD HOSSEIN | TARRAHI MOHAMMAD JAVAD | AMANI REZA | Issue Writer Certificate 

Pages

  17-22

Abstract

 Background: Infertility is a major worldwide problem which is caused by several factors such as environmental, physiological, and genetic conditions. Lycopene is considered to be one of the most important antioxidants that can contribute to reducing or preventing the psychological damage that leads to infertility. Thus, the aim of this study was to evaluate the effect of Lycopene supplementation on Depression, Anxiety and Stress scales and Quality of Life in infertile men. Materials and Methods: In this randomized clinical trial, 44 infertile men with oligozoospermia were randomly divided into the following two groups: the experimental group was supplemented with 25 mg Lycopene, once per day for 12 weeks, and the control group received a placebo, for 12 weeks. Anthropometric and dietary data, physical activity, mood status, including Depression, Anxiety, Stress, and Quality of Life scores were recorded pre-and post-intervention. Depression, Anxiety and Stress were assessed using a 21-item questionnaire (DASS-21) and Quality of Life was examined using the WHO 26-qustion questionnaire (WHOQOL). Results: The baseline age and body mass index (BMI) were not significantly different between the two groups (age: 31. 89 ± 2. 51 and 32. 15 ± 2. 16 years old for intervention and placebo, respectively; P=0. 732 and BMI: 27. 20 ± 1. 68 and 26. 53 ± 1. 53; for intervention and placebo, respectively; P=0. 206). There were no significant differences in Depression, Anxiety and Stress values between the two groups; however, Depression score significantly decreased in both groups compared to the baseline levels (P=0. 028 and P=0. 031). No significant differences were observed in four domains of Quality of Life, except for psychological domain that was improved in the Lycopene group compared to the baseline values (P=0. 049). Conclusion: Short term supplementation of Lycopene had no effect on mood status and Quality of Life, except for psychological status in infertile men.

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    Cite

    APA: Copy

    NOURI, MEHRAN, NASR ESFAHANI, MOHAMMAD HOSSEIN, TARRAHI, MOHAMMAD JAVAD, & AMANI, REZA. (2020). The Effect of Lycopene Supplementation on Mood Status and Quality of Life in Infertile Men: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 14(1), 17-22. SID. https://sid.ir/paper/306084/en

    Vancouver: Copy

    NOURI MEHRAN, NASR ESFAHANI MOHAMMAD HOSSEIN, TARRAHI MOHAMMAD JAVAD, AMANI REZA. The Effect of Lycopene Supplementation on Mood Status and Quality of Life in Infertile Men: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2020;14(1):17-22. Available from: https://sid.ir/paper/306084/en

    IEEE: Copy

    MEHRAN NOURI, MOHAMMAD HOSSEIN NASR ESFAHANI, MOHAMMAD JAVAD TARRAHI, and REZA AMANI, “The Effect of Lycopene Supplementation on Mood Status and Quality of Life in Infertile Men: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 14, no. 1, pp. 17–22, 2020, [Online]. Available: https://sid.ir/paper/306084/en

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