Case Report, Which One Is More Prominent in Recurrent Hydatidiform Mole, Ovum or Sperm?

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HAFEZI MARYAM; Chekini Zahra; ZAMANIAN MOHAMMADREZA

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Journal: International Journal of Fertility & Sterility Year:2020 | Volume:14 | Issue:2 Page(s): 154-158

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Title

Case Report, Which One Is More Prominent in Recurrent Hydatidiform Mole, Ovum or Sperm?

Author(s)

HAFEZI MARYAM | Chekini Zahra | ZAMANIAN MOHAMMADREZA | Issue Writer Certificate

Keywords

Hydatidiform Mole

Intracytoplasmic Sperm Injections

Ovum Donation

Preimplantation Genetic Diagnosis

Abstract

Recurrent Hydatidiform Mole is defined as episodes of two molar pregnancies in a female. Often, complete moles only derive androgenic nuclear genome. We described two cases with repeated molar pregnancies attempted to prevent future episodes by performing intracytoplasmic sperm injection (ICSI) and Preimplantation Genetic Diagnosis (PGD) to assess genetic disorders. The first patient had previously six complete molar pregnancies and advised to carry out ICSI with Ovum Donation to achieve a normal pregnancy. The second case had previously five molar pregnancies and no XY embryos from the ICSI/PGD process. We had to (at the insistence of the patient) transfer XX embryos in this patient which resulted in a complete Hydatidiform Mole (CHM). Hence, available data based on our patients and previous studies demonstrated that oocyte might play a critical role in the pathophysiology of recurrent Hydatidiform Mole, while it has not been often considered.

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APA: Copy

HAFEZI, MARYAM, Chekini, Zahra, & ZAMANIAN, MOHAMMADREZA. (2020). Case Report, Which One Is More Prominent in Recurrent Hydatidiform Mole, Ovum or Sperm?. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 14(2), 154-158. SID. https://sid.ir/paper/306094/en

Vancouver: Copy

HAFEZI MARYAM, Chekini Zahra, ZAMANIAN MOHAMMADREZA. Case Report, Which One Is More Prominent in Recurrent Hydatidiform Mole, Ovum or Sperm?. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2020;14(2):154-158. Available from: https://sid.ir/paper/306094/en

IEEE: Copy

MARYAM HAFEZI, Zahra Chekini, and MOHAMMADREZA ZAMANIAN, “Case Report, Which One Is More Prominent in Recurrent Hydatidiform Mole, Ovum or Sperm?,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 14, no. 2, pp. 154–158, 2020, [Online]. Available: https://sid.ir/paper/306094/en

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