HEPATITIS C VIRUS INFECTION AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE

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EROL S.; SAGLAM L.; OZBEK A.; KADANALI A.

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Journal Paper

Paper Information

Journal: Hepatitis Monthly Year:2009 | Volume:9 | Issue:1 (22) Page(s): 39-44

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Information Journal Paper

Title

HEPATITIS C VIRUS INFECTION AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Author(s)

EROL S. | SAGLAM L. | OZBEK A. | KADANALI A. | Issue Writer Certificate

Keywords

HEPATITIS C

CHRONIC OBSTRUCTIVE PULMONARY DISEASE

PREVALENCE

EXTRAHEPATIC MANIFESTATION

Abstract

Background and Aims: A growing pile of evidence supports the notion that pulmonary involvement is one of the EXTRAHEPATIC MANIFESTATIONs of chronic HEPATITIS C virus (HCV) infection. The objective of this study was to determine the PREVALENCE of HCV infection in patients with CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD), and vice versa. Methods: Two cross-sectional studies were performed: 1. A PREVALENCE study of HCV infection among patients with COPD; 2. A PREVALENCE study of COPD among patients with chronic HCV infection. COPD was diagnosed according to ATS/ERS guidelines. The PREVALENCE of HCV infection in COPD group was compared with the result of a previous study which determined the PREVALENCE of HCV infection in general population. PREVALENCE of COPD in patients with chronic HCV infection was also compared to those with chronic hepatitis B virus (HBV) infection.Results: The study included 108 patients with COPD, 68 patients with chronic HCV infection, and 60 patients with chronic HBV infection. HCV infection was observed in 8.3% of patients with COPD, and 1.2% of the control subjects (P= 0.000). The PREVALENCE of COPD among patients with chronic HCV and HBV infection was 17.6%, and 5%, respectively (P=0.03). Comparing COPD-positive and -negative chronic HCV patients for risk factors for COPD revealed that only the mean age was higher in COPD-positive patients (60.8±9.1 years vs. 46.5±11.5 years, P=0.000). In multivariate analysis, age was found to be the only independent predictor of COPD in HCV group. Conclusions: Patients with COPD have increased PREVALENCE of HCV infection, and patients with HCV infection, have increased PREVALENCE of COPD. COPD may be an extrahepatic disease associated with HCV infection.

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APA: Copy

EROL, S., SAGLAM, L., OZBEK, A., & KADANALI, A.. (2009). HEPATITIS C VIRUS INFECTION AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE. HEPATITIS MONTHLY, 9(1 (22)), 39-44. SID. https://sid.ir/paper/306210/en

Vancouver: Copy

EROL S., SAGLAM L., OZBEK A., KADANALI A.. HEPATITIS C VIRUS INFECTION AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE. HEPATITIS MONTHLY[Internet]. 2009;9(1 (22)):39-44. Available from: https://sid.ir/paper/306210/en

IEEE: Copy

S. EROL, L. SAGLAM, A. OZBEK, and A. KADANALI, “HEPATITIS C VIRUS INFECTION AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE,” HEPATITIS MONTHLY, vol. 9, no. 1 (22), pp. 39–44, 2009, [Online]. Available: https://sid.ir/paper/306210/en

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