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Information Journal Paper

Title

COMMENTARY ON: NONINVASIVE ASSESSMENT OF LIVER FIBROSIS USING ASPARTATE TRANSAMINASE TO PLATELET RATIO INDEX (APRI) IN ADULT PATIENTS WITH CHRONIC LIVER DISEASE (LETTER TO EDITOR)

Pages

  378-379

Abstract

 We enjoyed reading the excellent article by Yilmaz and colleagues on noninvasive assessment of liver fibrosis using aspartate transaminase to platelet ratio index (APRI) in adult patients with chronic liver disease (CLD) (1). They performed their tests on adults with CHRONIC HEPATITIS C (CHC), B (CHB), and non-alcoholic FATTY LIVER disease (NAFLD).We definitely need to develop serological markers that have satisfactory sensitivity, specificity, and high predictive values, which can be used either instead of liver biopsy or to reduce the frequency of needed biopsies for monitoring the evolution of CHC and defining the right moment for commencing treatment. Despite the study results showing that APRI has an acceptable accuracy for the assessment of liver fibrosis in adults with CHC and NAFLD, this was not the case in CHB patients. We believe that the study results would have been more valid if the researchers have used a combination of non-invasivetests to assess liver fibrosis. A similar study conducted in Hungary used APRI and liver stiffness (LS) measurements to assess fibrosis in CHC (2). The combination of both fibrosis markers was useful for non-invasive assessment of fibrosis in CHC. Forestier and colleagues found that LS measurements, APRI score, 13C-amniopyrine breath test and indocyanine green plasma clearance were reliable markers for assessing cirrhosis in patients with CLD (3).APRI was also found to be a simple and readily available tool for assessing liver fibrosis in patients with biliary atresia during post-operative follow-up care (4).

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    APA: Copy

    EL SHABRAWI, MORTADA, & ISA, MONA. (2011). COMMENTARY ON: NONINVASIVE ASSESSMENT OF LIVER FIBROSIS USING ASPARTATE TRANSAMINASE TO PLATELET RATIO INDEX (APRI) IN ADULT PATIENTS WITH CHRONIC LIVER DISEASE (LETTER TO EDITOR). HEPATITIS MONTHLY, 11(5 (34)), 378-379. SID. https://sid.ir/paper/306398/en

    Vancouver: Copy

    EL SHABRAWI MORTADA, ISA MONA. COMMENTARY ON: NONINVASIVE ASSESSMENT OF LIVER FIBROSIS USING ASPARTATE TRANSAMINASE TO PLATELET RATIO INDEX (APRI) IN ADULT PATIENTS WITH CHRONIC LIVER DISEASE (LETTER TO EDITOR). HEPATITIS MONTHLY[Internet]. 2011;11(5 (34)):378-379. Available from: https://sid.ir/paper/306398/en

    IEEE: Copy

    MORTADA EL SHABRAWI, and MONA ISA, “COMMENTARY ON: NONINVASIVE ASSESSMENT OF LIVER FIBROSIS USING ASPARTATE TRANSAMINASE TO PLATELET RATIO INDEX (APRI) IN ADULT PATIENTS WITH CHRONIC LIVER DISEASE (LETTER TO EDITOR),” HEPATITIS MONTHLY, vol. 11, no. 5 (34), pp. 378–379, 2011, [Online]. Available: https://sid.ir/paper/306398/en

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