HEPATITIS B IMMUNE GLOBULIN IN LIVER TRANSPLANTATION PROPHYLAXIS: AN UPDATE

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DINDOOST PAYAM; JAZAYERI SEYED MOHAMMAD; ALAVIAN SEYED MOAYED

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Journal Paper

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Journal: Hepatitis Monthly Year:2012 | Volume:12 | Issue:3 Page(s): 168-176

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Information Journal Paper

Title

HEPATITIS B IMMUNE GLOBULIN IN LIVER TRANSPLANTATION PROPHYLAXIS: AN UPDATE

Author(s)

DINDOOST PAYAM | JAZAYERI SEYED MOHAMMAD | ALAVIAN SEYED MOAYED | Issue Writer Certificate

Keywords

LIVER TRANSPLANTATION

HEPATITIS B HYPERIMMUNE GLOBULIN

PREVENTION AND CONTROL

Abstract

Context: LIVER TRANSPLANTATION is the best treatment option for end-stage liver disease following hepatitis B (HBV) infection. However, the high rate of recurrence of HBV infection following transplantation is a disadvantage of this option.Evidence Acquisition: Over the past 2 decades, the gold standard of prophylactic treatment for the prevention of HBV re-infection following LIVER TRANSPLANTATION has been the administration of low- to high-dose hepatitis B immune globulin (HBIg) along with an antiviral agent to induce passive immunity.Results: The effectiveness of HBIg in preventing the recurrence of HBV depends on the dosage, route of administration, and duration of HBIg treatment, and the viremic status at the time of transplantation. There is currently no consensus on a standardized recommendation for therapeutic options that include HBIg administration.Conclusion: This review attempts to summarize the available data on the feasibility of such options. Most recent studies support the use of long-term combination therapy of HBIg and antiviral NAs (especially new agents).

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APA: Copy

DINDOOST, PAYAM, JAZAYERI, SEYED MOHAMMAD, & ALAVIAN, SEYED MOAYED. (2012). HEPATITIS B IMMUNE GLOBULIN IN LIVER TRANSPLANTATION PROPHYLAXIS: AN UPDATE. HEPATITIS MONTHLY, 12(3), 168-176. SID. https://sid.ir/paper/306549/en

Vancouver: Copy

DINDOOST PAYAM, JAZAYERI SEYED MOHAMMAD, ALAVIAN SEYED MOAYED. HEPATITIS B IMMUNE GLOBULIN IN LIVER TRANSPLANTATION PROPHYLAXIS: AN UPDATE. HEPATITIS MONTHLY[Internet]. 2012;12(3):168-176. Available from: https://sid.ir/paper/306549/en

IEEE: Copy

PAYAM DINDOOST, SEYED MOHAMMAD JAZAYERI, and SEYED MOAYED ALAVIAN, “HEPATITIS B IMMUNE GLOBULIN IN LIVER TRANSPLANTATION PROPHYLAXIS: AN UPDATE,” HEPATITIS MONTHLY, vol. 12, no. 3, pp. 168–176, 2012, [Online]. Available: https://sid.ir/paper/306549/en

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