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Title

SERUM LEVELS OF ANTI-HEPATITIS B SURFACE ANTIBODY AMONG VACCINATED POPULATION AGED 1 TO 18 YEARS IN AHVAZ CITY SOUTHWEST OF IRAN

Pages

  1-5

Abstract

 Background: The duration of protection following primary series VACCINATION against HEPATITIS B is unknown in children and adolescents. It has been shown that the level of anti-HEPATITIS B surface antigen antibodies (anti HBs Ab) declines over years after VACCINATION.Objectives: The aim of this study was to estimate the long-term immunity against HEPATITIS B virus infection among children and adolescents who had received a complete HEPATITIS B VACCINATION series during infancy.Patients and Methods: In a cross-sectional study, the-anti-HBsAb levels of 840 vaccinated children and adolescents were determined by enzyme-linked immunosorbent assay.Results: HEPATITIS B seroprotection rates (anti HBsAb³10 IU/L) among vaccinated children and adolescents aged 1 and 18 years were 90% and 48.9%, respectively. The declining trend of geometric mean titer of anti-HBsAb levels was observed as changed from 272.3 IU/L to 94.1 IU/L in 1 and 18-year-old population, respectively. A significant negative correlation was found between age and anti-HBsAb levels (r=-0.220, P=0.0001).Conclusions: The results showed a declining trend in anti-HBsAb titers over the time after VACCINATION against HEPATITIS B virus in our region. Further studies are warranted to establish the need for a booster dose in cases that are at risk of HEPATITIS B virus infection.

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    APA: Copy

    NOROUZIRAD, REZA, SHAKURNIA, ABDOL HUSSEIN, ASSAREHZADEGAN, MOHAMMAD ALI, SERAJIAN, AMIRARSALAN, & KHABAZKHOOB, MEHDI. (2014). SERUM LEVELS OF ANTI-HEPATITIS B SURFACE ANTIBODY AMONG VACCINATED POPULATION AGED 1 TO 18 YEARS IN AHVAZ CITY SOUTHWEST OF IRAN. HEPATITIS MONTHLY, 14(1), 1-5. SID. https://sid.ir/paper/306598/en

    Vancouver: Copy

    NOROUZIRAD REZA, SHAKURNIA ABDOL HUSSEIN, ASSAREHZADEGAN MOHAMMAD ALI, SERAJIAN AMIRARSALAN, KHABAZKHOOB MEHDI. SERUM LEVELS OF ANTI-HEPATITIS B SURFACE ANTIBODY AMONG VACCINATED POPULATION AGED 1 TO 18 YEARS IN AHVAZ CITY SOUTHWEST OF IRAN. HEPATITIS MONTHLY[Internet]. 2014;14(1):1-5. Available from: https://sid.ir/paper/306598/en

    IEEE: Copy

    REZA NOROUZIRAD, ABDOL HUSSEIN SHAKURNIA, MOHAMMAD ALI ASSAREHZADEGAN, AMIRARSALAN SERAJIAN, and MEHDI KHABAZKHOOB, “SERUM LEVELS OF ANTI-HEPATITIS B SURFACE ANTIBODY AMONG VACCINATED POPULATION AGED 1 TO 18 YEARS IN AHVAZ CITY SOUTHWEST OF IRAN,” HEPATITIS MONTHLY, vol. 14, no. 1, pp. 1–5, 2014, [Online]. Available: https://sid.ir/paper/306598/en

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