مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

APOLIPOPROTEIN C3 GENE POLYMORPHISMS ARE NOT A RISK FACTOR FOR DEVELOPING NON-ALCOHOLIC FATTY LIVER DISEASE: A META-ANALYSIS

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  0-0

Abstract

 Context: Our objective was to evaluate the effect of gene POLYMORPHISMS of APOLIPOPROTEIN C3 (APOC3) on the development of non-alcoholic fatty liver disease (NAFLD) in different populations.Evidence Acquisition: We performed a meta-analysis of all relevant studies published in the literature. A total of 115 clinical trials or reports were identified, but only seven trials met our inclusion criteria. A meta-analysis was performed according to the Cochrane Reviewers’ Handbook recommendations.Results: Five hospital-based and two population-based case-control studies were included in the final analysis. The overall frequency of APOC3 gene POLYMORPHISMS was 67.5% (1177.1745) in NAFLD and 68.8% (988/1437) in controls. The summary odds ratio for the association of gene POLYMORPHISMS of APOC3 and the risk of NAFLD was 1.03 (95% CI: 0.89-1.22), which was not statistically significant (P>0.05).Conclusions: Our meta-analysis, while not ruling out possible publication bias, showed no association between gene POLYMORPHISMS of APOC3 and the risk of NAFLD development in different populations in the world.

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    APA: Copy

    ZHANG, HAIYING, CHEN, LIZHEN, XIN, YONGNING, LIU, YANG, & XUAN, SHIYING. (2014). APOLIPOPROTEIN C3 GENE POLYMORPHISMS ARE NOT A RISK FACTOR FOR DEVELOPING NON-ALCOHOLIC FATTY LIVER DISEASE: A META-ANALYSIS. HEPATITIS MONTHLY, 14(10), 0-0. SID. https://sid.ir/paper/306603/en

    Vancouver: Copy

    ZHANG HAIYING, CHEN LIZHEN, XIN YONGNING, LIU YANG, XUAN SHIYING. APOLIPOPROTEIN C3 GENE POLYMORPHISMS ARE NOT A RISK FACTOR FOR DEVELOPING NON-ALCOHOLIC FATTY LIVER DISEASE: A META-ANALYSIS. HEPATITIS MONTHLY[Internet]. 2014;14(10):0-0. Available from: https://sid.ir/paper/306603/en

    IEEE: Copy

    HAIYING ZHANG, LIZHEN CHEN, YONGNING XIN, YANG LIU, and SHIYING XUAN, “APOLIPOPROTEIN C3 GENE POLYMORPHISMS ARE NOT A RISK FACTOR FOR DEVELOPING NON-ALCOHOLIC FATTY LIVER DISEASE: A META-ANALYSIS,” HEPATITIS MONTHLY, vol. 14, no. 10, pp. 0–0, 2014, [Online]. Available: https://sid.ir/paper/306603/en

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