PLASMA ZINC LEVEL IN HEPATITIS C PATIENTS WITH OR WITHOUT BETA THALASSEMIA MAJOR, IS THERE ANY DIFFERENCE?

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ABBASINAZARI MOHAMMAD; BEHNAVA BITA; PANAHI YUNES; HAJHOSSEIN TALASAZ AZITA; SALIMI SHIMA; KESHVARI MARYAM; MEHRNOUSH LEILA; KARIMI ELIZEE PEGAH; GHOLAMI FESHARAKI MOHAMMAD; ASGHARINIA MANSOUR; ALAVIAN SEYED MOAYED

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Journal: Hepatitis Monthly Year:2013 | Volume:13 | Issue:8 Page(s): 1-3

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Title

PLASMA ZINC LEVEL IN HEPATITIS C PATIENTS WITH OR WITHOUT BETA THALASSEMIA MAJOR, IS THERE ANY DIFFERENCE?

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Keywords

ZINC

BETA-THALASSEMIA

HEPATITIS C

IRAN

Abstract

Background: ZINC deficiency has been reported frequently in HEPATITIS C patients in the literature. Furthermore, a decrease in ZINC level has been shown in beta thalassemia major as well. IRANians consume a large amount of phytate in their regimens which can bind with ZINC and decrease its gastrointestinal absorption.Objectives: This study was designed to determine plasma ZINC level in an IRANian sample with the diagnosis of HEPATITIS C with or without concomitant beta thalassemia major.Patients and Methods: Between April 2011 and April 2012, plasma ZINC level was determined via atomic absorption method, in 130 HEPATITIS C patients with or without beta thalassemia major in a known referral center of hepatic diseases in Tehran, IRAN.Results: Mean±standard deviation (SD) of plasma ZINC levels was determined as 0.78 ± 0.22 mg/L. Also ZINC level was 0.76±0.19 mg/L and 0.80±0.24 mg/L in thalassemic and non thalassemic patients, respectively. T-test analysis showed that there is no significant difference between these two groups regarding plasma ZINC level (P=0.235).Conclusions: It is concluded that ZINC level of studied patients is less than which is reported in normal IRANian population. Moreover, there is not a significant difference in plasma ZINC levels between thalassemic and non thalassemic patients and it seems to be a common problem in both ones. Addition of ZINC supplement may be recommended in both groups in order to optimize the nutritional support and probably improve the treatment response.

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APA: Copy

ABBASINAZARI, MOHAMMAD, BEHNAVA, BITA, PANAHI, YUNES, HAJHOSSEIN TALASAZ, AZITA, SALIMI, SHIMA, KESHVARI, MARYAM, MEHRNOUSH, LEILA, KARIMI ELIZEE, PEGAH, GHOLAMI FESHARAKI, MOHAMMAD, ASGHARINIA, MANSOUR, & ALAVIAN, SEYED MOAYED. (2013). PLASMA ZINC LEVEL IN HEPATITIS C PATIENTS WITH OR WITHOUT BETA THALASSEMIA MAJOR, IS THERE ANY DIFFERENCE?. HEPATITIS MONTHLY, 13(8), 1-3. SID. https://sid.ir/paper/306682/en

Vancouver: Copy

ABBASINAZARI MOHAMMAD, BEHNAVA BITA, PANAHI YUNES, HAJHOSSEIN TALASAZ AZITA, SALIMI SHIMA, KESHVARI MARYAM, MEHRNOUSH LEILA, KARIMI ELIZEE PEGAH, GHOLAMI FESHARAKI MOHAMMAD, ASGHARINIA MANSOUR, ALAVIAN SEYED MOAYED. PLASMA ZINC LEVEL IN HEPATITIS C PATIENTS WITH OR WITHOUT BETA THALASSEMIA MAJOR, IS THERE ANY DIFFERENCE?. HEPATITIS MONTHLY[Internet]. 2013;13(8):1-3. Available from: https://sid.ir/paper/306682/en

IEEE: Copy

MOHAMMAD ABBASINAZARI, BITA BEHNAVA, YUNES PANAHI, AZITA HAJHOSSEIN TALASAZ, SHIMA SALIMI, MARYAM KESHVARI, LEILA MEHRNOUSH, PEGAH KARIMI ELIZEE, MOHAMMAD GHOLAMI FESHARAKI, MANSOUR ASGHARINIA, and SEYED MOAYED ALAVIAN, “PLASMA ZINC LEVEL IN HEPATITIS C PATIENTS WITH OR WITHOUT BETA THALASSEMIA MAJOR, IS THERE ANY DIFFERENCE?,” HEPATITIS MONTHLY, vol. 13, no. 8, pp. 1–3, 2013, [Online]. Available: https://sid.ir/paper/306682/en

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