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Title

ANTI-HEPATITIS E ANTIBODY IN HEMODIALYSIS PATIENTS IN ISFAHAN, IRAN: PREVALENCE AND RISK FACTORS

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Abstract

 Background: Many studies have been performed regarding the PREVALENCE of HEPATITIS E in the general population, but there is controversial evidence for an increased risk of the infection in patients on maintenance HEMODIALYSIS (HD).Objectives: The primary end point of the present study was to determine if the PREVALENCE of anti-hepatitis E virus IgG (anti-HEV IgG) is higher in patients on maintenance HD than in the normal population in Isfahan.Patients and Methods: In a case-control study performed in Isfahan in June 2012, we compared the seroprevalence of HEV among 274 patients on maintenance HD and 275 otherwise healthy individuals. The patients were recruited from 3 HD centers in Isfahan. Anti-HEV IgG was detected using a Dia Pro Diagnostic HEV enzyme immunoassay (ELISA) kit. Demographic and clinical data (sex, age, blood transfusion history, HD duration, age at HD initiation, and evidence of hepatitis B and hepatitis C infections) were obtained from the medical records of the HD patients.Results: Anti-HEV IgG was detected in 27 (9.9%) controls and 78 (28.3%) patients, with the difference being statistically significant (P < 0.05). Furthermore, there was a significant association between positive anti-HEV antibody, HD duration, and blood transfusion history in the HD patients.Conclusions: Considering the results, it seems necessary to conduct prospective studies in order to identify factors responsible for the high seroprevalence of HEV in Isfahan HD units.

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    APA: Copy

    ALAVIAN, SEYED MOAYED, ATAEI, BEHROOZ, EBRAHIMI, ALI, PIRHAJI, OMID, AZAD, ROYA, OLYA, BEHROOZ, & ATAEI, AMIR MOHAMMAD. (2015). ANTI-HEPATITIS E ANTIBODY IN HEMODIALYSIS PATIENTS IN ISFAHAN, IRAN: PREVALENCE AND RISK FACTORS. HEPATITIS MONTHLY, 15(9), 0-0. SID. https://sid.ir/paper/306936/en

    Vancouver: Copy

    ALAVIAN SEYED MOAYED, ATAEI BEHROOZ, EBRAHIMI ALI, PIRHAJI OMID, AZAD ROYA, OLYA BEHROOZ, ATAEI AMIR MOHAMMAD. ANTI-HEPATITIS E ANTIBODY IN HEMODIALYSIS PATIENTS IN ISFAHAN, IRAN: PREVALENCE AND RISK FACTORS. HEPATITIS MONTHLY[Internet]. 2015;15(9):0-0. Available from: https://sid.ir/paper/306936/en

    IEEE: Copy

    SEYED MOAYED ALAVIAN, BEHROOZ ATAEI, ALI EBRAHIMI, OMID PIRHAJI, ROYA AZAD, BEHROOZ OLYA, and AMIR MOHAMMAD ATAEI, “ANTI-HEPATITIS E ANTIBODY IN HEMODIALYSIS PATIENTS IN ISFAHAN, IRAN: PREVALENCE AND RISK FACTORS,” HEPATITIS MONTHLY, vol. 15, no. 9, pp. 0–0, 2015, [Online]. Available: https://sid.ir/paper/306936/en

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