GENOTYPE 4 HEPATITIS E VIRUS PREVALENT IN EASTERN CHINA SHOWS DIVERSE SUBTYPES

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

TIAN HUA; FU XINGLI; LI WANG; HUANG YUAN; SUN JIAYAO; ZHOU GAI; ZHOU CHENGLIN; SHEN QUAN; YANG SHIXING; ZHANG WEN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Hepatitis Monthly Year:2015 | Volume:15 | Issue:6 Page(s): 0-0

Download Full-Text

View:

270

Download:

244

Cites:

Information Journal Paper

Title

GENOTYPE 4 HEPATITIS E VIRUS PREVALENT IN EASTERN CHINA SHOWS DIVERSE SUBTYPES

Author(s)

Keywords

HEPATITIS E VIRUS

GENOTYPE

SUBTYPE

GENETIC DIVERSITY

Abstract

Background: HEPATITIS E VIRUS (HEV), a zoonotic pathogen, uses several species of animal as reservoirs. Swine is considered as the major reservoir for HEV infection in humans. GENOTYPE 4 HEV is the dominant cause of hepatitis E disease in humans in China.Objectives: Although many researches revealed that GENOTYPE 4 HEV is the main GENOTYPE that prevalent in eastern China, few researches have done to study the SUBTYPE of HEV in this area. Thus, this study aimed to investigate the SUBTYPE of HEV prevalent in eastern China.Materials and Methods: A total of 125 anti-HEV IgM positive human serum and 290 swine fecal samples were subjected to reverse transcription polymerase chain reaction (RT-PCR) screening of HEV RNA. Positive PCR products were sequenced and phylogenetic ally analyzed.Results: From a total of 125 human serum samples, 19.2% (24.125) were positive, while 9.66% (28.290) of the 290 swine fecal samples were positive for HEV RNA. Phylogenetic analysis based on partial capsid gene showed that the 51 HEV strains in the current study all belonged to GENOTYPE 4, clustering into 6 different SUBTYPEs. Our results also revealed that some of HEV isolates prevalent in the human and swine populations were classified into the same clusters.Conclusions: GENOTYPE 4 HEV in eastern China shows SUBTYPE diversity and some HEV isolates are involved in cross-species transmission.

Cites

No record.

References

No record.

Cite

APA: Copy

TIAN, HUA, FU, XINGLI, LI, WANG, HUANG, YUAN, SUN, JIAYAO, ZHOU, GAI, ZHOU, CHENGLIN, SHEN, QUAN, YANG, SHIXING, & ZHANG, WEN. (2015). GENOTYPE 4 HEPATITIS E VIRUS PREVALENT IN EASTERN CHINA SHOWS DIVERSE SUBTYPES. HEPATITIS MONTHLY, 15(6), 0-0. SID. https://sid.ir/paper/306946/en

Vancouver: Copy

TIAN HUA, FU XINGLI, LI WANG, HUANG YUAN, SUN JIAYAO, ZHOU GAI, ZHOU CHENGLIN, SHEN QUAN, YANG SHIXING, ZHANG WEN. GENOTYPE 4 HEPATITIS E VIRUS PREVALENT IN EASTERN CHINA SHOWS DIVERSE SUBTYPES. HEPATITIS MONTHLY[Internet]. 2015;15(6):0-0. Available from: https://sid.ir/paper/306946/en

IEEE: Copy

HUA TIAN, XINGLI FU, WANG LI, YUAN HUANG, JIAYAO SUN, GAI ZHOU, CHENGLIN ZHOU, QUAN SHEN, SHIXING YANG, and WEN ZHANG, “GENOTYPE 4 HEPATITIS E VIRUS PREVALENT IN EASTERN CHINA SHOWS DIVERSE SUBTYPES,” HEPATITIS MONTHLY, vol. 15, no. 6, pp. 0–0, 2015, [Online]. Available: https://sid.ir/paper/306946/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops