IMMUNOHISTOCHEMICAL DETECTION OF APOPTOTIC FACTORS BAX AND BCL-2 IN THE LUNG ALVEOLI FOLLOWING SIX WEEKS OF HIGH INTENSITY EXERCISE TRAINING

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

YADEGARI MEHDI; RIAHY SIMIN; MIRDAR SHADMEHR; HAMIDIYAN GHOLAM REZA; YOUSEFPOUR MITRA; Riyahi Fatemeh

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: DANESHVAR MEDICINE Year:2017 | Volume:24 | Issue:129 Page(s): 31-40

Download Full-Text

Persian Verion

View:

1,206

Download:

Cites:

Information Journal Paper

Title

IMMUNOHISTOCHEMICAL DETECTION OF APOPTOTIC FACTORS BAX AND BCL-2 IN THE LUNG ALVEOLI FOLLOWING SIX WEEKS OF HIGH INTENSITY EXERCISE TRAINING

Author(s)

Keywords

HIGH INTENSITY INTERVAL TRAININGQ1

APOPTOSISQ1

BAXQ2

BCL-2Q1

LUNGQ2

Abstract

Background and Objective: From the perspective of molecular studies, since the relationship between HIGH INTENSITY INTERVAL TRAINING and APOPTOSIS-related proteins in the LUNGs has not investigated, aim of this study was immunohistochemical detection of apoptotic proteins BAX and BCL-2 in the LUNGs alveoli after 6 weeks of HIGH INTENSITY INTERVAL TRAINING.Materials and Methods: This research was an experimental study. Samples of this study were 14 male Wistar rats (4 weeks old, 72±8 gr weight), healthy and no history of disease that divided into training and control groups (exercise training=7, control=7). The HIGH INTENSITY INTERVAL TRAINING program was carried out for 6 weeks. Training program was started with 25 m/min and ended with 70 m/min speed at the final stage. In each training session, rats completed the 1-min activity with 10 repetition and work to rest ratio was 1: 2. LUNG tissue was extracted for Immunohistochemistry tests and protein levels of BAX and BCL-2 were measured. To analyze data, independent t- test was used (P<0.05).Results: After 6 weeks of HIGH INTENSITY INTERVAL TRAINING, level of BAX protein significantly increased. Also, after 6 weeks of HIGH INTENSITY INTERVAL TRAINING, level of BCL-2 protein also significantly increased (P<0.05).Conclusion: It seems that intensity interval training period causes significant changes in expression of pulmonary alveolar apoptotic proteins and its accurate interpretation that it may be helpful or harmful require further researches.

Cites

No record.

References

Cite

APA: Copy

YADEGARI, MEHDI, RIAHY, SIMIN, MIRDAR, SHADMEHR, HAMIDIYAN, GHOLAM REZA, YOUSEFPOUR, MITRA, & Riyahi, Fatemeh. (2017). IMMUNOHISTOCHEMICAL DETECTION OF APOPTOTIC FACTORS BAX AND BCL-2 IN THE LUNG ALVEOLI FOLLOWING SIX WEEKS OF HIGH INTENSITY EXERCISE TRAINING. DANESHVAR MEDICINE, 24(129), 31-40. SID. https://sid.ir/paper/30755/en

Vancouver: Copy

YADEGARI MEHDI, RIAHY SIMIN, MIRDAR SHADMEHR, HAMIDIYAN GHOLAM REZA, YOUSEFPOUR MITRA, Riyahi Fatemeh. IMMUNOHISTOCHEMICAL DETECTION OF APOPTOTIC FACTORS BAX AND BCL-2 IN THE LUNG ALVEOLI FOLLOWING SIX WEEKS OF HIGH INTENSITY EXERCISE TRAINING. DANESHVAR MEDICINE[Internet]. 2017;24(129):31-40. Available from: https://sid.ir/paper/30755/en

IEEE: Copy

MEHDI YADEGARI, SIMIN RIAHY, SHADMEHR MIRDAR, GHOLAM REZA HAMIDIYAN, MITRA YOUSEFPOUR, and Fatemeh Riyahi, “IMMUNOHISTOCHEMICAL DETECTION OF APOPTOTIC FACTORS BAX AND BCL-2 IN THE LUNG ALVEOLI FOLLOWING SIX WEEKS OF HIGH INTENSITY EXERCISE TRAINING,” DANESHVAR MEDICINE, vol. 24, no. 129, pp. 31–40, 2017, [Online]. Available: https://sid.ir/paper/30755/en

Related Journal Papers