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Title

BACTERIURIA BY EXTENDED-SPECTRUM BETA-LACTAMASE- PRODUCING ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIAE ISOLATES IN A GOVERNMENTAL HOSPITAL IN SOUTH OF TEHRAN, IRAN

Pages

  197-200

Abstract

 Introduction. Antibiotic resistant mutants producing extendedspectrum beta-lactamase (ESBL) have emerged among Escherichia coli AND KLEBSIELLA PNEUMONIAE. This study was done to determine the frequency of ESBL-producing E coli and K pneumoniae species isolated from urine samples of our patients. Materials and Methods. A study was conducted on 164 urine isolates (124 E coli and 40 K pneumoniae) in the laboratory Loghman Hakim Hospital in Tehran, Iran, in 2007. Microbial sensitivity tests were done on Mueller-Hinton agar plates with disk diffusion method. Broad-spectrum resistance was defined as resistance to ampicillin or cephalothin; ESBL resistance, as resistance of these bacteria to one of ceftriaxone, ceftazidime, or ceftizoxime; and MDR-ESBL; as resistance to 3 of the following antibiotic groups: trimethoprim-sulfamethoxazole, aminoglycosides, fluoroquinolones, and nitrofurantoin.Results. An ESBL resistance was detected in 52.5% of isolates with K pneumoniae and 45.2% of those with E coli. The MDR-ESBL pattern was detected in 26.8% of the isolates. These included 30.0% of the K pneumoniae and 25.8% of the E coli isolates. Broad-spectrum resistance was detected in all K pneumoniae isolates and 87.9% of 124 E coli isolates.Conclusions. Our study showed a high rate of ESBL resistant strain of E coli and K pneumoniae and the emergency of MULTIPLE DRUG RESISTANCE to these bacteria in our patients in Tehran, Iran.

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    APA: Copy

    AMINZADEH, ZOHREH, KASHI, M.S., & SHAABANI, MINOUSH. (2008). BACTERIURIA BY EXTENDED-SPECTRUM BETA-LACTAMASE- PRODUCING ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIAE ISOLATES IN A GOVERNMENTAL HOSPITAL IN SOUTH OF TEHRAN, IRAN. IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD), 2(4), 197-200. SID. https://sid.ir/paper/308710/en

    Vancouver: Copy

    AMINZADEH ZOHREH, KASHI M.S., SHAABANI MINOUSH. BACTERIURIA BY EXTENDED-SPECTRUM BETA-LACTAMASE- PRODUCING ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIAE ISOLATES IN A GOVERNMENTAL HOSPITAL IN SOUTH OF TEHRAN, IRAN. IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD)[Internet]. 2008;2(4):197-200. Available from: https://sid.ir/paper/308710/en

    IEEE: Copy

    ZOHREH AMINZADEH, M.S. KASHI, and MINOUSH SHAABANI, “BACTERIURIA BY EXTENDED-SPECTRUM BETA-LACTAMASE- PRODUCING ESCHERICHIA COLI AND KLEBSIELLA PNEUMONIAE ISOLATES IN A GOVERNMENTAL HOSPITAL IN SOUTH OF TEHRAN, IRAN,” IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD), vol. 2, no. 4, pp. 197–200, 2008, [Online]. Available: https://sid.ir/paper/308710/en

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