THE EFFECT OF FLAVONOIDS ON THE BASAL AND ACTIVE TONICITY OF THE AORTIC RINGS IN NORMAL AND DIABETIC RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ROUGHANI M.; MAHDAVI M.V.; MOJARRAD T.B.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: DANESHVAR MEDICINE Year:2006 | Volume:13 | Issue:63 Page(s): 35-40

Download Full-Text

Persian Verion

View:

806

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF FLAVONOIDS ON THE BASAL AND ACTIVE TONICITY OF THE AORTIC RINGS IN NORMAL AND DIABETIC RATS

Author(s)

ROUGHANI M. | MAHDAVI M.V. | MOJARRAD T.B. | Issue Writer Certificate

Keywords

QUERCETINQ1

DIABETES MELLITUSQ3

VASCULAR TONEQ3

RATQ2

Abstract

Introduction: Vascular dysfunctions have been a well-established complication of DIABETES MELLITUS. Flavonoids, including QUERCETIN, have been proposed as one of the main treatment strategies to prevent diabetic complications. This study was conducted to evaluate the possible vasoactive effect of QUERCETIN on the basal and active tone of aortic rings from streptozotocin (STZ)-diabetic RATs.Materials & Methods: Vascular responsiveness of noreadrenaline-precontracted isolated rings of thoracic aorta from control and streptozotocin-diabetic RATs was recorded after 4 weeks, by using isolated tissue setup.Results: The findings showed that although QUERCETIN could not make a significant difference in the basal tone of the aortic rings, in both control and diabetic groups; it was capable of producing a significant dosedependent vasorelaxation in aortic rings precontracted with noradrenalin (NA) in the diabetic group as compared to the control group (p<0.01). Conclusion: Vasorelaxant effect of QUERCETIN is developed only in noreadrenaline-precontracted aortic rings in normal and diabetic RATs and there is no such effect on the basal tonicity of the aorta.

Cites

No record.

References

No record.

Cite

APA: Copy

ROUGHANI, M., MAHDAVI, M.V., & MOJARRAD, T.B.. (2006). THE EFFECT OF FLAVONOIDS ON THE BASAL AND ACTIVE TONICITY OF THE AORTIC RINGS IN NORMAL AND DIABETIC RATS. DANESHVAR MEDICINE, 13(63), 35-40. SID. https://sid.ir/paper/30891/en

Vancouver: Copy

ROUGHANI M., MAHDAVI M.V., MOJARRAD T.B.. THE EFFECT OF FLAVONOIDS ON THE BASAL AND ACTIVE TONICITY OF THE AORTIC RINGS IN NORMAL AND DIABETIC RATS. DANESHVAR MEDICINE[Internet]. 2006;13(63):35-40. Available from: https://sid.ir/paper/30891/en

IEEE: Copy

M. ROUGHANI, M.V. MAHDAVI, and T.B. MOJARRAD, “THE EFFECT OF FLAVONOIDS ON THE BASAL AND ACTIVE TONICITY OF THE AORTIC RINGS IN NORMAL AND DIABETIC RATS,” DANESHVAR MEDICINE, vol. 13, no. 63, pp. 35–40, 2006, [Online]. Available: https://sid.ir/paper/30891/en

Related Journal Papers