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Information Journal Paper

Title

CONNEXINS, CELL PROLIFERATION AND SECOND MESSENGERS IN THE CRYSTALLINE LENS (SUNY EYE INSTITUTE PROCEEDINGS)

Pages

  107-108

Keywords

Not Registered.

Abstract

 Gap junctions are responsible for the direct coupling of cells that enables intercellular exchange of ions, small metabolites and second messengers. Lens epithelial cells are well coupled (Fig.1a) by connexin (Cx) channels that constitute the structural subunits of gap junctions.Surprisingly, epithelial cell proliferation during the early postnatal period (Fig.1b) was found to be profoundly influenced by the type of connexin subunit present in the gap junction channels between cells. The loss, or functional replacement, of Cx50 caused a significant decrease in the number of dividing cells during the first postnatal week, suggesting that Cx50-mediated communication was essential for peak mitosis to occur.

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  • Cite

    APA: Copy

    WHITE, THOMAS W.. (2012). CONNEXINS, CELL PROLIFERATION AND SECOND MESSENGERS IN THE CRYSTALLINE LENS (SUNY EYE INSTITUTE PROCEEDINGS). JOURNAL OF OPHTHALMIC AND VISION RESEARCH, 7(1), 107-108. SID. https://sid.ir/paper/311486/en

    Vancouver: Copy

    WHITE THOMAS W.. CONNEXINS, CELL PROLIFERATION AND SECOND MESSENGERS IN THE CRYSTALLINE LENS (SUNY EYE INSTITUTE PROCEEDINGS). JOURNAL OF OPHTHALMIC AND VISION RESEARCH[Internet]. 2012;7(1):107-108. Available from: https://sid.ir/paper/311486/en

    IEEE: Copy

    THOMAS W. WHITE, “CONNEXINS, CELL PROLIFERATION AND SECOND MESSENGERS IN THE CRYSTALLINE LENS (SUNY EYE INSTITUTE PROCEEDINGS),” JOURNAL OF OPHTHALMIC AND VISION RESEARCH, vol. 7, no. 1, pp. 107–108, 2012, [Online]. Available: https://sid.ir/paper/311486/en

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