STUDY ON EFFECTS OF INHALATED TOLUENE, NOISE AND TOLUENE ALONG WITH NOISE (FREQUENCIES 250-2000 HZ) PER AUDITORY BRAIN STEM RESPONSE (ABR) ON RABBIT

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KHAVANIN A.; MORTAZAVI S.B.; MIRZAEI RAMEZAN; FATH ELAHI Y.; KAZEMNEJAD ANOUSHIRAVAN; AKBARI MAHDI

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Journal: Daneshvar Medicine: Basic and Clinical Research Journal Year:2008 | Volume:15 | Issue:76 Page(s): 7-14

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Title

STUDY ON EFFECTS OF INHALATED TOLUENE, NOISE AND TOLUENE ALONG WITH NOISE (FREQUENCIES 250-2000 HZ) PER AUDITORY BRAIN STEM RESPONSE (ABR) ON RABBIT

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Keywords

AUDITORY BRAINSTEM RESPONSEQ3

RABBITQ3

TOLUENEQ3

NOISEQ3

Abstract

Introduction: In the present study, was performed to investigate the relationship between TOLUENE(1000 ppm), NOISE, TOLUENE and TOLUENE along with NOISE (frequencies 250- 2000 Hz) per auditory Brain Stem response (ABR) on RABBITs in which being exposed to this contaminants.Materials & Methods: Three months old, male adult white New Zealand RABBITs (1400-1700 g body weight) were used throughout this study. The groups were divided according to type of exposure summarized as follows: group 1, controls (unexposed); group 2, exposed to TOLUENE(1000 ppm); group 3, NOISE exposure (100 dB SPL, 250HZ, 8 h/day, 5days/week), 100 dB SPL; group 4, TOLUENE (1000 ppm) and NOISE exposure (250HZ, 8 h/day, 5days/week), group 5, NOISE exposure (500Hz); group 6 TOLUENE and NOISE exposure (500HZ), group 7, NOISE exposure (1000Hz); group 8, TOLUENE and NOISE exposure (1000HZ); group 9, NOISE exposure (2000Hz); group 10, TOLUENE and NOISE exposure (2000HZ). Sound pressure level in the chamber was measured using a Bruel and Kjaer 2231 sound level meter (Denmark) and TOLUENE concentration was measured with gas chromatograph. RABBITs based on their hearing ability were measured by AUDITORY BRAINSTEM RESPONSE (ABR).Results: A low and mid frequencies (250,500 and 1000Hz) auditory impairment was observed following exposure to TOLUENE alone and NOISE alone. TOLUENE followed by NOISE resulted in a higher threshold at all frequencies. The latencies of V wave (5th wave) increased after treatments.Conclusion: Exposure of RABBITs to only TOLUENE made hearing impairment whereas TOLUENE and NOISE exposure (100 dB SPL, 250 Hz - 2000Hz, 8 h/day, 5days/week) were worse than hearing impairment.

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APA: Copy

KHAVANIN, A., MORTAZAVI, S.B., MIRZAEI, RAMEZAN, FATH ELAHI, Y., KAZEMNEJAD, ANOUSHIRAVAN, & AKBARI, MAHDI. (2008). STUDY ON EFFECTS OF INHALATED TOLUENE, NOISE AND TOLUENE ALONG WITH NOISE (FREQUENCIES 250-2000 HZ) PER AUDITORY BRAIN STEM RESPONSE (ABR) ON RABBIT. DANESHVAR MEDICINE, 15(76), 7-14. SID. https://sid.ir/paper/31184/en

Vancouver: Copy

KHAVANIN A., MORTAZAVI S.B., MIRZAEI RAMEZAN, FATH ELAHI Y., KAZEMNEJAD ANOUSHIRAVAN, AKBARI MAHDI. STUDY ON EFFECTS OF INHALATED TOLUENE, NOISE AND TOLUENE ALONG WITH NOISE (FREQUENCIES 250-2000 HZ) PER AUDITORY BRAIN STEM RESPONSE (ABR) ON RABBIT. DANESHVAR MEDICINE[Internet]. 2008;15(76):7-14. Available from: https://sid.ir/paper/31184/en

IEEE: Copy

A. KHAVANIN, S.B. MORTAZAVI, RAMEZAN MIRZAEI, Y. FATH ELAHI, ANOUSHIRAVAN KAZEMNEJAD, and MAHDI AKBARI, “STUDY ON EFFECTS OF INHALATED TOLUENE, NOISE AND TOLUENE ALONG WITH NOISE (FREQUENCIES 250-2000 HZ) PER AUDITORY BRAIN STEM RESPONSE (ABR) ON RABBIT,” DANESHVAR MEDICINE, vol. 15, no. 76, pp. 7–14, 2008, [Online]. Available: https://sid.ir/paper/31184/en

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