FREQUENCY OF HEPATITIS C IN PATIENTS WITH RHEUMATOID ARTHRITIS

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EHSANI ARDAKANI M.J.; RAJAEI A.R.; MOHAGHEGH SHALMANI H.; SHAHID N.; EMAM M.M.; MOHAMMADZADEH N.A.; MIRHASANI MOGHADAM S.J.; ZALI MOHAMMAD REZA

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Journal: IRANIAN JOURNAL OF CLINICAL INFECTIOUS DISEASES Year:2009 | Volume:4 | Issue:1 Page(s): 39-43

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Title

FREQUENCY OF HEPATITIS C IN PATIENTS WITH RHEUMATOID ARTHRITIS

Author(s)

Keywords

HEPATITIS C

RHEUMATOID ARTHRITIS

HCV-RNA

RT-PCR

Abstract

Background: HEPATITIS C virus (HCV) infection has been explained as a disease that sometimes present with rheumatic manifestations indistinguishable from RHEUMATOID ARTHRITIS. This study has been performed to evaluate the frequency of HEPATITIS C virus infection in a group of patients with RHEUMATOID ARTHRITIS.Patients and methods: In this study, during one year, serum samples collected from two hundred consecutive patients with RHEUMATOID ARTHRITIS in all affiliated hospitals of Shaheed Beheshti University, M.C., were examined for anti-HCV antibody and HCV-RNA by ELISA and RT-PCR method, respectively. Using a questionnaire, the frequency of HCV infection, age and sex distribution, duration of RHEUMATOID ARTHRITIS, associated immune mediated disorders and risk factors for HEPATITIS C virus infection were assessed.Results: A total of 200 patients (M/F=26/174) who were mainly aged 51-70 years were studied. The frequency of HCV was found to be 2% (95%CI: 0.6-7%). All of the infected persons have had a low risk occupation in terms of exposure to the virus and none of them had HCV risk factors. No associated immune mediated disorder was found in HCV infected patients.Conclusion: Our results did not support any contribution of HCV infection in the pathogenesis of RHEUMATOID ARTHRITIS.

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APA: Copy

EHSANI ARDAKANI, M.J., RAJAEI, A.R., MOHAGHEGH SHALMANI, H., SHAHID, N., EMAM, M.M., MOHAMMADZADEH, N.A., MIRHASANI MOGHADAM, S.J., & ZALI, MOHAMMAD REZA. (2009). FREQUENCY OF HEPATITIS C IN PATIENTS WITH RHEUMATOID ARTHRITIS. IRANIAN JOURNAL OF CLINICAL INFECTIOUS DISEASES, 4(1), 39-43. SID. https://sid.ir/paper/313497/en

Vancouver: Copy

EHSANI ARDAKANI M.J., RAJAEI A.R., MOHAGHEGH SHALMANI H., SHAHID N., EMAM M.M., MOHAMMADZADEH N.A., MIRHASANI MOGHADAM S.J., ZALI MOHAMMAD REZA. FREQUENCY OF HEPATITIS C IN PATIENTS WITH RHEUMATOID ARTHRITIS. IRANIAN JOURNAL OF CLINICAL INFECTIOUS DISEASES[Internet]. 2009;4(1):39-43. Available from: https://sid.ir/paper/313497/en

IEEE: Copy

M.J. EHSANI ARDAKANI, A.R. RAJAEI, H. MOHAGHEGH SHALMANI, N. SHAHID, M.M. EMAM, N.A. MOHAMMADZADEH, S.J. MIRHASANI MOGHADAM, and MOHAMMAD REZA ZALI, “FREQUENCY OF HEPATITIS C IN PATIENTS WITH RHEUMATOID ARTHRITIS,” IRANIAN JOURNAL OF CLINICAL INFECTIOUS DISEASES, vol. 4, no. 1, pp. 39–43, 2009, [Online]. Available: https://sid.ir/paper/313497/en

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