ASSOCIATION BETWEEN DIABETIC RETINOPATHY AND LEFT VENTRICULAR DYSFUNCTION IN DIABETIC PATIENTS WITH UNSTABLE ANGINA

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HEYDARI EBAD ELAH; NEMATZADEH PAKDEL SANAZ; SAMADIKHAH JAHANBAKHSH; AZARFARIN RASOUL; SHADVAR KAMRAN

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Journal: Journal of Cardiovascular and Thoracic Research Year:2012 | Volume:4 | Issue:4 Page(s): 113-117

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Title

ASSOCIATION BETWEEN DIABETIC RETINOPATHY AND LEFT VENTRICULAR DYSFUNCTION IN DIABETIC PATIENTS WITH UNSTABLE ANGINA

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Keywords

UNSTABLE ANGINA

DIABETIC RETINOPATHY

LEFT VENTRICULAR EJECTION FRACTION

Abstract

Introduction: Diabetes mellitus (DM) is associated with serious complications including macro- and microvascular problems such as DIABETIC RETINOPATHY. Coronary involvement in diabetic patients is believed to be a consequence of microvascular complications. However, the available data are inconclusive and scarce. This study aimed to evaluate the probable association between DIABETIC RETINOPATHY and left ventricular dysfunction in diabetic patients with UNSTABLE ANGINA (UA).Methods: In this cross-sectional study, 200 diabetic patients with UA (100 cases with DIABETIC RETINOPATHY and 100 cases without DIABETIC RETINOPATHY) were enrolled in a teaching hospital. LEFT VENTRICULAR EJECTION FRACTION (LVEF) as well as the frequency of cases with left ventricular dysfunction (LVEF<50%) were compared between the two groups and different degrees of DIABETIC RETINOPATHY (proliferative and non-proliferative).Results: Patients’ demographic variables were comparable between the two groups. Mean diagnosistime of DM was significantly higher in the patients with DIABETIC RETINOPATHY (8.40±6.60 vs.3.81±3.58 years; P<0.001). Mean LVEFwas significantly lower in the retinopathy group (50.50±6.91% vs.53.07±4.87%; P=0.003). Frequency of cases with left ventricular dysfunction wassignificantly higher in the group with DIABETIC RETINOPATHY (31% vs.12%; P=0.001, OR=3.33, 95%CI: 1.58-7.14). The frequency of cases with left ventricular dysfunction was significantly yet independently higherin patients with proliferative vs. non-proliferative DIABETIC RETINOPATHY.Conclusion: Left ventricular dysfunction is more common in diabetic patients with UNSTABLE ANGINA and DIABETIC RETINOPATHY compared with their counterparts without DIABETIC RETINOPATHY.

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APA: Copy

HEYDARI, EBAD ELAH, NEMATZADEH PAKDEL, SANAZ, SAMADIKHAH, JAHANBAKHSH, AZARFARIN, RASOUL, & SHADVAR, KAMRAN. (2012). ASSOCIATION BETWEEN DIABETIC RETINOPATHY AND LEFT VENTRICULAR DYSFUNCTION IN DIABETIC PATIENTS WITH UNSTABLE ANGINA. JOURNAL OF CARDIOVASCULAR AND THORACIC RESEARCH, 4(4), 113-117. SID. https://sid.ir/paper/314908/en

Vancouver: Copy

HEYDARI EBAD ELAH, NEMATZADEH PAKDEL SANAZ, SAMADIKHAH JAHANBAKHSH, AZARFARIN RASOUL, SHADVAR KAMRAN. ASSOCIATION BETWEEN DIABETIC RETINOPATHY AND LEFT VENTRICULAR DYSFUNCTION IN DIABETIC PATIENTS WITH UNSTABLE ANGINA. JOURNAL OF CARDIOVASCULAR AND THORACIC RESEARCH[Internet]. 2012;4(4):113-117. Available from: https://sid.ir/paper/314908/en

IEEE: Copy

EBAD ELAH HEYDARI, SANAZ NEMATZADEH PAKDEL, JAHANBAKHSH SAMADIKHAH, RASOUL AZARFARIN, and KAMRAN SHADVAR, “ASSOCIATION BETWEEN DIABETIC RETINOPATHY AND LEFT VENTRICULAR DYSFUNCTION IN DIABETIC PATIENTS WITH UNSTABLE ANGINA,” JOURNAL OF CARDIOVASCULAR AND THORACIC RESEARCH, vol. 4, no. 4, pp. 113–117, 2012, [Online]. Available: https://sid.ir/paper/314908/en

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