مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Title

EFFECTS OF PROBIOTICS ON BIOMARKERS OF OXIDATIVE STRESS AND INFLAMMATORY FACTORS IN PETROCHEMICAL WORKERS: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL

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Abstract

 Background: The aim of the current study was to determine effects of probiotic yoghurt and multispecies probiotic capsule supplementation on biomarkers of OXIDATIVE STRESS and inflammatory factors in PETROCHEMICAL WORKERS.Methods: This randomized, double-blind, placebo-controlled trial was done among PETROCHEMICAL WORKERS. Subjects were randomly divided into three groups to receive 100 g/day probiotic yogurt (n = 12) or one probiotic capsule daily (n = 13) or 100 g/day conventional yogurt (n = 10) for 6 weeks. The probiotic yoghurt was containing two strains of Lactobacillus acidophilus and Bifidobacterium lactis with a total of min 1 × 107 CFU. Multispecies probiotic capsule contains seven probiotic bacteria spices Actobacillus casei 3 × 103, L. acidophilus 3 × 107, Lactobacillus rhamnosus 7 × 109, Lactobacillus bulgaricus 5 × 108, Bifidobacterium breve 2 × 1010, Bifidobacterium longum 1 × 109 and Streptococcus thermophilus 3 × 108 CFU/g. Fasting blood samples were obtained at the beginning and end of the trial to quantify biomarkers of OXIDATIVE STRESS and inflammatory factors.Results: Although a significant within-group decrease in plasma PROTEIN CARBONYL levels was seen in the probiotic capsule group (326.0 ± 308.9 vs. 251.0 ± 176.3 ng/mL, P = 0.02), the changes were similar among the three groups. In addition, significant within-group decreases in plasma ISO PROSTAGLANDIN were observed in the probiotic supplements group (111.9 ± 85.4 vs. 88.0 ± 71.0 pg/ mL, P = 0.003) and in the probiotic yogurt group (116.3 ± 93.0 vs. 92.0 ± 66.0 pg/mL, P = 0.02), nevertheless there were no significant change among the three groups.Conclusions: Taken together, consumption of probiotic yogurt or multispecies probiotic capsule had beneficial effects on biomarkers of OXIDATIVE STRESS in PETROCHEMICAL WORKERS.

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    APA: Copy

    MOHAMMADI, ALI AKBAR, JAZAYERI, SHIMA, KHOSRAVI DARANI, KIANOUSH, SOLATI, ZAHRA, MOHAMMADPOUR, NAKISA, ASEMI, ZATOLLAH, ADAB, ZOHRE, DJALALI, MAHMOUD, TEHRANI DOOST, MEHDI, HOSSEINI, MOSTAFA, & EGHTESADI, SHAHRYAR. (2015). EFFECTS OF PROBIOTICS ON BIOMARKERS OF OXIDATIVE STRESS AND INFLAMMATORY FACTORS IN PETROCHEMICAL WORKERS: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL. INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE, 6(9), 0-0. SID. https://sid.ir/paper/316264/en

    Vancouver: Copy

    MOHAMMADI ALI AKBAR, JAZAYERI SHIMA, KHOSRAVI DARANI KIANOUSH, SOLATI ZAHRA, MOHAMMADPOUR NAKISA, ASEMI ZATOLLAH, ADAB ZOHRE, DJALALI MAHMOUD, TEHRANI DOOST MEHDI, HOSSEINI MOSTAFA, EGHTESADI SHAHRYAR. EFFECTS OF PROBIOTICS ON BIOMARKERS OF OXIDATIVE STRESS AND INFLAMMATORY FACTORS IN PETROCHEMICAL WORKERS: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL. INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE[Internet]. 2015;6(9):0-0. Available from: https://sid.ir/paper/316264/en

    IEEE: Copy

    ALI AKBAR MOHAMMADI, SHIMA JAZAYERI, KIANOUSH KHOSRAVI DARANI, ZAHRA SOLATI, NAKISA MOHAMMADPOUR, ZATOLLAH ASEMI, ZOHRE ADAB, MAHMOUD DJALALI, MEHDI TEHRANI DOOST, MOSTAFA HOSSEINI, and SHAHRYAR EGHTESADI, “EFFECTS OF PROBIOTICS ON BIOMARKERS OF OXIDATIVE STRESS AND INFLAMMATORY FACTORS IN PETROCHEMICAL WORKERS: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL,” INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE, vol. 6, no. 9, pp. 0–0, 2015, [Online]. Available: https://sid.ir/paper/316264/en

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