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Information Journal Paper

Title

DISTRIBUTIONS AND TYPES OF MULTIDRUG-RESISTANT ACINETOBACTER BAUMANNII IN DIFFERENT DEPARTMENTS OF A GENERAL HOSPITAL

Pages

  1-7

Abstract

 Background: ACINETOBACTER BAUMANNII is the most prevalent strain in hospitals and different clinical departments.Objectives: The current study aimed to investigate the genetic characteristics and resistance mechanisms of A. baumannii isolated from clinical samples in Shaoxing people’s hospital affiliated to Zhejiang University, Shaoxing, China.Patients and Methods: ACINETOBACTER BAUMANNII strains were isolated from blood, phlegm and skin of the patients hospitalized in different departments as respiratory medicine, plastic surgery and intensive care unit (ICU). MULTILOCUS SEQUENCE TYPING (MLST) was used to characterize the isolates. Kirby-Bauer test was used to evaluate ANTIBIOTIC RESISTANCE of the bacteria. The expression of resistance inducing genes was detected by reverse transcription polymerase chain reaction (RT-PCR). The results were analyzed and compared.Results: Two bacterial types, ST208, and ST218, were identified in all 140 samples. The ST208 mainly came from ICU and department of respiratory medicine, while ST218 from department of plastic surgery; 70.21% of ST208 and 84.78% of ST218 were carbapenem-resistant ACINETOBACTER BAUMANNII (CRAB) and carbapenem-susceptible ACINETOBACTER BAUMANNII (CSAB), respectively. Multidrug-resistance genes in CRAB isolated from the hospital mainly included, oxa-23, oxa-5, intl 1 and qace∆1-sul 1. Besides, the highest and lowest ANTIBIOTIC RESISTANCE was observed in the strains isolated from blood samples and wounds, respectively.Conclusions: The distribution of AB varies in different clinical departments and samples. In the hospital under study, the main types of AB were ST208 and ST218. The genes which affect the ability of antibiotic-resistance were oxa-23, oxa-51, intl 1 and qaceΔ1-sul 1.

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    APA: Copy

    QIAN, YANER, DONG, XUEJUN, WANG, ZONGXIN, YANG, GUOCAN, & LIU, QI. (2015). DISTRIBUTIONS AND TYPES OF MULTIDRUG-RESISTANT ACINETOBACTER BAUMANNII IN DIFFERENT DEPARTMENTS OF A GENERAL HOSPITAL . JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM), 8(9), 1-7. SID. https://sid.ir/paper/317477/en

    Vancouver: Copy

    QIAN YANER, DONG XUEJUN, WANG ZONGXIN, YANG GUOCAN, LIU QI. DISTRIBUTIONS AND TYPES OF MULTIDRUG-RESISTANT ACINETOBACTER BAUMANNII IN DIFFERENT DEPARTMENTS OF A GENERAL HOSPITAL . JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM)[Internet]. 2015;8(9):1-7. Available from: https://sid.ir/paper/317477/en

    IEEE: Copy

    YANER QIAN, XUEJUN DONG, ZONGXIN WANG, GUOCAN YANG, and QI LIU, “DISTRIBUTIONS AND TYPES OF MULTIDRUG-RESISTANT ACINETOBACTER BAUMANNII IN DIFFERENT DEPARTMENTS OF A GENERAL HOSPITAL ,” JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM), vol. 8, no. 9, pp. 1–7, 2015, [Online]. Available: https://sid.ir/paper/317477/en

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