In Vitro Susceptibilities of Non-albicans Candida Species to Echinocandins, Azoles, and Amphotericin B in Tokat, Turkey

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

YENISEHIRLI GULGUN; Ozveren Gulsen; YENISEHIRLI AYDAN; BULUT YUNUS

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Jundishapur Journal of Microbiology Year:2018 | Volume:11 | Issue:6 Page(s): 0-0

Download Full-Text

View:

166

Download:

152

Cites:

Information Journal Paper

Title

In Vitro Susceptibilities of Non-albicans Candida Species to Echinocandins, Azoles, and Amphotericin B in Tokat, Turkey

Author(s)

YENISEHIRLI GULGUN | Ozveren Gulsen | YENISEHIRLI AYDAN | BULUT YUNUS | Issue Writer Certificate

Keywords

Antifungal Agent

Susceptibility

Non albicans-Candida Species

Abstract

Background: Prophylactic and therapeutic uses of Antifungal Agents have given rise to a significant shift to more resistant nonalbicans Candida species associated with fungal infections. Objectives: This study aimed at identifying the distribution and antifungal Susceptibility patterns of non-albicans Candida spp. isolated from clinical specimens in Tokat, Turkey. Methods: The authors determined the Susceptibility of 103 non-albicans Candida isolates to the following Antifungal Agents: amphotericin B, anidulafungin, caspofungin, fluconazole, ketoconazole, itraconazole, voriconazole, and posaconazole, using the Etest method. Interpretation of Susceptibility was carried out using species specific breakpoints suggested by the Clinical and Laboratory Standards Institute (CLSI) M27-S4 document. Results: The most frequently isolated non-albicans Candida species were Candida kefyr (44 isolates, 42. 8%) followed by C. tropicalis (36 isolates, 35%), C. parapsilosis (17 isolates, 16. 5%), C. glabrata (four isolates, 3. 8%) and C. famata (two isolates, 1. 9%). None of the strains had MIC values of > 2 g/mL for amphotericin B except three of the 44 C. kefyr isolates. Resistance to caspofungin and anidulafungin were not detected in C. tropicalis, C. parapsilosis, and C. glabrata isolates. Only two of the 36 C. tropicalis isolates were categorized as intermediate resistant to anidulafungin, according to the new CLSI criteria. None of the C. parapsilosis isolates were found to be resistant to azole drugs. Conclusions: Most of the non-albicans Candida species were found to be susceptible to tested antifungal drugs. Therefore, use of routine Antifungal Agents like amphotericin B and fluconazole, which are available in this region, are suggested.

Cites

No record.

References

No record.

Cite

APA: Copy

YENISEHIRLI, GULGUN, Ozveren, Gulsen, YENISEHIRLI, AYDAN, & BULUT, YUNUS. (2018). In Vitro Susceptibilities of Non-albicans Candida Species to Echinocandins, Azoles, and Amphotericin B in Tokat, Turkey. JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM), 11(6), 0-0. SID. https://sid.ir/paper/317743/en

Vancouver: Copy

YENISEHIRLI GULGUN, Ozveren Gulsen, YENISEHIRLI AYDAN, BULUT YUNUS. In Vitro Susceptibilities of Non-albicans Candida Species to Echinocandins, Azoles, and Amphotericin B in Tokat, Turkey. JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM)[Internet]. 2018;11(6):0-0. Available from: https://sid.ir/paper/317743/en

IEEE: Copy

GULGUN YENISEHIRLI, Gulsen Ozveren, AYDAN YENISEHIRLI, and YUNUS BULUT, “In Vitro Susceptibilities of Non-albicans Candida Species to Echinocandins, Azoles, and Amphotericin B in Tokat, Turkey,” JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM), vol. 11, no. 6, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/317743/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops