Effects of High Intensity Interval Training and Combined Training on Serum Apelin Levels and pancreatic β-cell function in Overweight Type 2 Diabetes Women

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TAGHIPOUR ASRAMI AMIR; Ghaedi Hadi; BANITALEBI EBRAHIM

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Journal Paper

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Journal: Iranian Journal of Diabetes and Obesity Year:2018 | Volume:10 | Issue:4 Page(s): 178-186

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Title

Effects of High Intensity Interval Training and Combined Training on Serum Apelin Levels and pancreatic β-cell function in Overweight Type 2 Diabetes Women

Author(s)

TAGHIPOUR ASRAMI AMIR | Ghaedi Hadi | BANITALEBI EBRAHIM | Issue Writer Certificate

Keywords

Apelin

pancreatic β-cells function

Diabetes mellitus

High intensity interval training

Combined training

Abstract

Objective: Physical exercise is a well-established therapeutic method in type 2 diabetes treatment. The purpose of this study was to investigate the effects of eight weeks combined and High intensity interval training on serum Apelin levels and pancreatic β-cell function in overweight women with type 2 Diabetes mellitus. Materials and Methods: Fifty-two overweight female patients with type 2 diabetes (aged 45-60 years old, BMI> 30) with HbA1c>6. 5% participated in the study voluntarily. The participants were assigned to High intensity interval training (HIIT) group (n= 17), Combined training group (n= 17), and control group (n= 18) according to their HbA1c levels. The exercises included 12 weeks of Combined training and HIIT. Levels of HbA1c and fasting glucose and insulin were measured. Results: There was a significant decrease in the fasting blood glucose in the HIIT groups (P-value: 0. 001). Serum insulin levels showed significant increases in the HIIT (P-value: 0. 001) and Combined training groups (P-value: 0. 001). Changes in Apelin level were not significantly different within HIIT and Combined training groups (P-value: 0. 13 and 0. 09, respectively). The data showed significant differences in pancreatic β-cells function in HIIT (P < 0. 001) and Combined training groups (P= 0. 003). Furthermore, the ANCOVA test showed that there were no significant differences in fasting blood glucose concentrations (F= 1. 853, P-value: 0. 171), Apelin (F= 0. 511, P-value: 0. 12). However, significant differences were observed between groups in insulin (F= 3. 622, P-value: 0. 036), and β-cell function (F= 4. 243, P-value: 0. 003). Conclusion: Physical exercise is an effective training method to improve glycemic control in woman with type 2 diabetes.

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APA: Copy

TAGHIPOUR ASRAMI, AMIR, Ghaedi, Hadi, & BANITALEBI, EBRAHIM. (2018). Effects of High Intensity Interval Training and Combined Training on Serum Apelin Levels and pancreatic β-cell function in Overweight Type 2 Diabetes Women. IRANIAN JOURNAL OF DIABETES AND OBESITY, 10(4), 178-186. SID. https://sid.ir/paper/318235/en

Vancouver: Copy

TAGHIPOUR ASRAMI AMIR, Ghaedi Hadi, BANITALEBI EBRAHIM. Effects of High Intensity Interval Training and Combined Training on Serum Apelin Levels and pancreatic β-cell function in Overweight Type 2 Diabetes Women. IRANIAN JOURNAL OF DIABETES AND OBESITY[Internet]. 2018;10(4):178-186. Available from: https://sid.ir/paper/318235/en

IEEE: Copy

AMIR TAGHIPOUR ASRAMI, Hadi Ghaedi, and EBRAHIM BANITALEBI, “Effects of High Intensity Interval Training and Combined Training on Serum Apelin Levels and pancreatic β-cell function in Overweight Type 2 Diabetes Women,” IRANIAN JOURNAL OF DIABETES AND OBESITY, vol. 10, no. 4, pp. 178–186, 2018, [Online]. Available: https://sid.ir/paper/318235/en

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