EVALUATION OF FIBRINOLYTIC AND ANTIOXIDANT EFFECTS OF ALLIUM AFFINE HYDROALCOHOLIC EXTRACT

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SADEGHI MASOUD; SAFAEIAN LEILA; AGHAYE GHAZVINI MOHAMMADREZA; RAMEZANI MOJTABA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: RESEARCH IN PHARMACEUTICAL SCIENCES (RPS) Year:2017 | Volume:12 | Issue:4 Page(s): 299-306

Download Full-Text

View:

230

Download:

Cites:

Information Journal Paper

Title

EVALUATION OF FIBRINOLYTIC AND ANTIOXIDANT EFFECTS OF ALLIUM AFFINE HYDROALCOHOLIC EXTRACT

Author(s)

SADEGHI MASOUD | SAFAEIAN LEILA | AGHAYE GHAZVINI MOHAMMADREZA | RAMEZANI MOJTABA | Issue Writer Certificate

Keywords

ALLIUM AFFINE

ANTIOXIDANT

FIBRINOLYTIC AGENTS

Abstract

ALLIUM AFFINEis a member of Amaryllidaceae family, which grows wildly in some western regions of Iran.Limited information is available about the pharmacological activities of this plant. The present study aimed to evaluate thefibrinolytic and ANTIOXIDANT effects of hydroalcoholic extract of A. affine aerial parts. The in vitro ANTIOXIDANT properties of the extract were evaluated by total phenolic content assay, 1, 1-diphenyl-2-picrylhydrazyl (DPPH) scavenging activity and ferric reducing ANTIOXIDANT power (FRAP) assay. Thein vivo studies included the determination of hydroperoxides level and FRAP value in serum samples of rats receiving i.p. injections of the plant extract for 21 days. The fibrinolytic activity of the extract was quantitatively evaluated by measuring the clot weight. In vitro ANTIOXIDANT analysis exhibited the promising potential of DPPH scavenging and total ANTIOXIDANT capacity of A. affine extract. In the in vivo analysis, A. affine extract reduced the serum hydroperoxides level and increased the serum total ANTIOXIDANT capacity in rats. In vitro fibrinolytic assay also elucidated notable thrombolytic activity of the plant extract. The results of this study revealed the valuable ANTIOXIDANT and in vitro fibrinolytic activities of A. affine extract. Further studies are needed for better evaluation of anticoagulant and thrombolytic activities of this plant and understanding its detailed mechanisms.

Cites

No record.

References

No record.

Cite

APA: Copy

SADEGHI, MASOUD, SAFAEIAN, LEILA, AGHAYE GHAZVINI, MOHAMMADREZA, & RAMEZANI, MOJTABA. (2017). EVALUATION OF FIBRINOLYTIC AND ANTIOXIDANT EFFECTS OF ALLIUM AFFINE HYDROALCOHOLIC EXTRACT. RESEARCH IN PHARMACEUTICAL SCIENCES (RPS), 12(4), 299-306. SID. https://sid.ir/paper/318459/en

Vancouver: Copy

SADEGHI MASOUD, SAFAEIAN LEILA, AGHAYE GHAZVINI MOHAMMADREZA, RAMEZANI MOJTABA. EVALUATION OF FIBRINOLYTIC AND ANTIOXIDANT EFFECTS OF ALLIUM AFFINE HYDROALCOHOLIC EXTRACT. RESEARCH IN PHARMACEUTICAL SCIENCES (RPS)[Internet]. 2017;12(4):299-306. Available from: https://sid.ir/paper/318459/en

IEEE: Copy

MASOUD SADEGHI, LEILA SAFAEIAN, MOHAMMADREZA AGHAYE GHAZVINI, and MOJTABA RAMEZANI, “EVALUATION OF FIBRINOLYTIC AND ANTIOXIDANT EFFECTS OF ALLIUM AFFINE HYDROALCOHOLIC EXTRACT,” RESEARCH IN PHARMACEUTICAL SCIENCES (RPS), vol. 12, no. 4, pp. 299–306, 2017, [Online]. Available: https://sid.ir/paper/318459/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops