مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

ADULT-ONSET FAMILIAL MEDITERRANEAN FEVER IN NORTHWESTERN IRAN; CLINICAL FEATURE AND TREATMENT OUTCOME

Pages

  50-55

Abstract

 Background FAMILIAL MEDITERRANEAN FEVER (FMF) is an autosomal recessive disorder characterized by sporadic, paroxysmal attacks of fever and serosal inflammation. Although the disease usually begins before the age of 20 years, we aimed to evaluate the demography, CLINICAL FEATURES and TREATMENT outcome of FAMILIAL MEDITERRANEAN FEVER in Iranian adult patients above 20 years old.Methods In this cross-sectional study, adult patients (first attack at the age of >20 years) with a diagnosis of FMF who referred to the gastroenterology and rheumatology Clinics of Ardebil University of Medical Science (situated in north west of Iran) over the period of 2004-2009 were enrolled. FMF diagnosis was based on clinical criteria.Results Forty four FMF patients (30 male and 14 female) with the mean [±Standard Deviation (SD)] age of first attack of 29±7.8 years were enrolled. Abdominal pain (95.5%) and fever (91%) were the most common clinical findings. All of the patients had satisfactorily responded to therapy. Response was complete in 76.7% and partial in 23.3% of the patients. There was no clinical or laboratory evidence of amyloidosis at the time of diagnosis or during follow-up.Conclusion Our findings demonstrated that adult-onset FMF in Iran has different characteristics (more common in males, lesser prevalence of arthritis and erysipelas-like erythema, less delay in diagnosis) and TREATMENT outcome (favorable response even to low-dose colchicine) in comparison with the previous data on early onset patients.

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    • Cite

    APA: Copy

    NOBAKHT, H., ZAMANI, F., AJDARKOSH, H., MOHAMADZADEH, Z., FERESHTEHNEJAD, S.M., & NASSAJI, M.. (2011). ADULT-ONSET FAMILIAL MEDITERRANEAN FEVER IN NORTHWESTERN IRAN; CLINICAL FEATURE AND TREATMENT OUTCOME. MIDDLE EAST JOURNAL OF DIGESTIVE DISEASES (MEJDD), 3(1), 50-55. SID. https://sid.ir/paper/319050/en

    Vancouver: Copy

    NOBAKHT H., ZAMANI F., AJDARKOSH H., MOHAMADZADEH Z., FERESHTEHNEJAD S.M., NASSAJI M.. ADULT-ONSET FAMILIAL MEDITERRANEAN FEVER IN NORTHWESTERN IRAN; CLINICAL FEATURE AND TREATMENT OUTCOME. MIDDLE EAST JOURNAL OF DIGESTIVE DISEASES (MEJDD)[Internet]. 2011;3(1):50-55. Available from: https://sid.ir/paper/319050/en

    IEEE: Copy

    H. NOBAKHT, F. ZAMANI, H. AJDARKOSH, Z. MOHAMADZADEH, S.M. FERESHTEHNEJAD, and M. NASSAJI, “ADULT-ONSET FAMILIAL MEDITERRANEAN FEVER IN NORTHWESTERN IRAN; CLINICAL FEATURE AND TREATMENT OUTCOME,” MIDDLE EAST JOURNAL OF DIGESTIVE DISEASES (MEJDD), vol. 3, no. 1, pp. 50–55, 2011, [Online]. Available: https://sid.ir/paper/319050/en

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