مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

TARGET ANTIGENS FOR PERINUCLEAR ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES IN IRANIAN PATIENTS WITH ULCERATIVE COLITIS

Pages

  203-207

Abstract

 BACKGROUND: Patients with ULCERATIVE COLITIS (UC) carry autoantibodies such as perinuclear antineutrophil cytoplasmic antibodies (p-ANCA).Objective: The aim of the present study was to evaluate the target antigens for p-ANCA in Iranian patients with UC.METHODS: p-ANCA target antigens including elastase, lactoferrin, cathepsin G, myeloproxidase, lysozyme, and bactericidal permeability increasing protein (BPI) were determined in 113 patients with UC using enzyme-linked immunosorbent assay (ELISA).RESULTS: 59.2% of the patients were positive for at least one antigen and p-ANCA directed against lactoferrin, elastase, lysozyme, cathepsin G, Bactericidal permeability increasing protein, and myeloproxidase in 31.5%, 25.9%, 8.3%, 7.4%, 5.6%, and 0% of the patients, respectively.CONCLUSION: The highest prevalence of p-ANCA was observed against lactoferrin and elastase. Also, myeloproxidase was not an antigen for p-ANCA among our patients.

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    APA: Copy

    BAHARI, ALI, ARABI, MAHMOUD, HEDAYATI, MEHDI, JAROLLAHI, ALI, FIROUZI, FARZAD, AGHAZADEH, RAHIM, ZALI, MOHAMMAD REZA, BARI, ZOHREH, HASHEMI, MOHAMMAD, ESMAEILZADEH, ABBAS, MOKHTARIFAR, ALI, & GANJI, AZITA. (2014). TARGET ANTIGENS FOR PERINUCLEAR ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES IN IRANIAN PATIENTS WITH ULCERATIVE COLITIS. MIDDLE EAST JOURNAL OF DIGESTIVE DISEASES (MEJDD), 6(4), 203-207. SID. https://sid.ir/paper/319095/en

    Vancouver: Copy

    BAHARI ALI, ARABI MAHMOUD, HEDAYATI MEHDI, JAROLLAHI ALI, FIROUZI FARZAD, AGHAZADEH RAHIM, ZALI MOHAMMAD REZA, BARI ZOHREH, HASHEMI MOHAMMAD, ESMAEILZADEH ABBAS, MOKHTARIFAR ALI, GANJI AZITA. TARGET ANTIGENS FOR PERINUCLEAR ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES IN IRANIAN PATIENTS WITH ULCERATIVE COLITIS. MIDDLE EAST JOURNAL OF DIGESTIVE DISEASES (MEJDD)[Internet]. 2014;6(4):203-207. Available from: https://sid.ir/paper/319095/en

    IEEE: Copy

    ALI BAHARI, MAHMOUD ARABI, MEHDI HEDAYATI, ALI JAROLLAHI, FARZAD FIROUZI, RAHIM AGHAZADEH, MOHAMMAD REZA ZALI, ZOHREH BARI, MOHAMMAD HASHEMI, ABBAS ESMAEILZADEH, ALI MOKHTARIFAR, and AZITA GANJI, “TARGET ANTIGENS FOR PERINUCLEAR ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES IN IRANIAN PATIENTS WITH ULCERATIVE COLITIS,” MIDDLE EAST JOURNAL OF DIGESTIVE DISEASES (MEJDD), vol. 6, no. 4, pp. 203–207, 2014, [Online]. Available: https://sid.ir/paper/319095/en

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