EPIDEMIOLOGICAL STUDY OF THE PATIENTS REFERRED FOR THALASSEMIA DIAGNOSIS USING CHORIONIC VILLOUS SAMPLING (CVS) IN GENETIC LABORATORY OF DASTGHEIB HOSPITAL, SHIRAZ, 2011

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GHAHRAMANI FARIBA; REZAEI MOHAMMAD AMIN; AFRASIABI ABDOLREZA; GOHAR NEJAD JAMALLEDIN

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Journal Paper

Paper Information

Journal: JOURNAL OF FAMILY AND REPRODUCTIVE HEALTH Year:2012 | Volume:6 | Issue:3 Page(s): 111-114

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Title

EPIDEMIOLOGICAL STUDY OF THE PATIENTS REFERRED FOR THALASSEMIA DIAGNOSIS USING CHORIONIC VILLOUS SAMPLING (CVS) IN GENETIC LABORATORY OF DASTGHEIB HOSPITAL, SHIRAZ, 2011

Author(s)

GHAHRAMANI FARIBA | REZAEI MOHAMMAD AMIN | AFRASIABI ABDOLREZA | GOHAR NEJAD JAMALLEDIN | Issue Writer Certificate

Keywords

THAHLASSEMIA

GENETIC

CHORIONIC VILLOUS SAMPLING

LABORATORY

Abstract

Objective: Pre-natal diagnosis is the most effected way to prevent GENETIC diseases in a society. The aim of this research was to show the prevention level of the birth of the children with major thalassemia disorder and the demographic condition of the people referring to the Shahid Dastgheib GENETIC Center in Shiraz for the pre natal diagnosis.Materials and methods: The present research was a cross- sectional (descriptive, analytical) one. In this study, the amount of sampling was done by census in a way that all the case (372 cases) related to the year 2010. The questionnaire was prepared based on the information present in the files. In order to compare the quantitative and qualitative variables, two sample t - test and K sample t- test were used.Results: Out of 372 fetuses tested, 25.5% had major thalassemia, 48.7% minor thalassemia, 0.8% intermediate, 1.3% sickle cell, and 23.7% were healthy. All the cases diagnosed with thalassemia were introduced for abortion, and abortion was carried out. Major thalassemia was more prevalent in Lore tribes (32.9%), which was more in comparison to the members of others tribes.Conclusion: In order to prevent major thalassemia, it is important to identify the gene carriers and prevent their marriage. Nevertheless, in many places in the country, especially in the villages and rural areas, the couples do the experiment after they have already gotten emotionally involved and made the arrangements to get married; therefore they’ re unwilling to stop the marriage. As a result, post-nuptial CVS during pregnancy is crucial.

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APA: Copy

GHAHRAMANI, FARIBA, REZAEI, MOHAMMAD AMIN, AFRASIABI, ABDOLREZA, & GOHAR NEJAD, JAMALLEDIN. (2012). EPIDEMIOLOGICAL STUDY OF THE PATIENTS REFERRED FOR THALASSEMIA DIAGNOSIS USING CHORIONIC VILLOUS SAMPLING (CVS) IN GENETIC LABORATORY OF DASTGHEIB HOSPITAL, SHIRAZ, 2011. JOURNAL OF FAMILY AND REPRODUCTIVE HEALTH, 6(3), 111-114. SID. https://sid.ir/paper/320865/en

Vancouver: Copy

GHAHRAMANI FARIBA, REZAEI MOHAMMAD AMIN, AFRASIABI ABDOLREZA, GOHAR NEJAD JAMALLEDIN. EPIDEMIOLOGICAL STUDY OF THE PATIENTS REFERRED FOR THALASSEMIA DIAGNOSIS USING CHORIONIC VILLOUS SAMPLING (CVS) IN GENETIC LABORATORY OF DASTGHEIB HOSPITAL, SHIRAZ, 2011. JOURNAL OF FAMILY AND REPRODUCTIVE HEALTH[Internet]. 2012;6(3):111-114. Available from: https://sid.ir/paper/320865/en

IEEE: Copy

FARIBA GHAHRAMANI, MOHAMMAD AMIN REZAEI, ABDOLREZA AFRASIABI, and JAMALLEDIN GOHAR NEJAD, “EPIDEMIOLOGICAL STUDY OF THE PATIENTS REFERRED FOR THALASSEMIA DIAGNOSIS USING CHORIONIC VILLOUS SAMPLING (CVS) IN GENETIC LABORATORY OF DASTGHEIB HOSPITAL, SHIRAZ, 2011,” JOURNAL OF FAMILY AND REPRODUCTIVE HEALTH, vol. 6, no. 3, pp. 111–114, 2012, [Online]. Available: https://sid.ir/paper/320865/en

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