مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

STEADY STATE HEMOGLOBIN CONCENTRATION AND PACKED CELL VOLUME IN HOMOZYGOUS SICKLE CELL DISEASE PATIENTS IN LAGOS, NIGERIA

Pages

  405-409

Abstract

 Background: Sickle cell disease is a genetic disorder of hemoglobin causing myriad of pathology including anemia. The purpose of this study was to evaluate the baseline values of STEADY STATE hemoglobin and PACKED CELL VOLUME as a guide to managing the early recognition of hemolytic crises in sickle cell anemia.Methods: A cross-sectional study was conducted among the sickle cell patients attending the Sickle Cell clinic of Lagos State University Teaching Hospital, Ikeja. A blood sample of 4.5 ml blood was collected from each participant for HEMOGLOBIN CONCENTRATION and PACKED CELL VOLUME. All blood samples were also screened for HIV and hemoglobin phenotypes were done using cellulose acetate hemoglobin electrophoresis at pH 8.6.Results: A total of 98 subjects in STEADY STATE were recruited, consisting of 53 (54.1%) females and 45 (45.9%) males. The overall means were 7.92±1.49 and 24.46±4.76; a female mean of 7.73±1.45; 23.89±4.60, and a male mean of 8.14±1.54 and 25.14±4.91 were obtained for hemoglobin and PACKED CELL VOLUME, respectively. Sixty – nine of the 98 (70.40%) subjects have been previously transfused with blood.Conclusion: The mean HEMOGLOBIN CONCENTRATION and PACKED CELL VOLUME in males was higher than females. The overall mean was lower than what was expected for age and sex. Over two-third of sickle cell anemia population had been transfused.

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    APA: Copy

    AKINBAMI, AKINSEGUN, DOSUNMU, ADEDOYIN, ADEDIRAN, ADEWUMI, OSHINAIKE, OLAJUMOKE, PHILLIP, ADEBOLA, VINCENT, OSUNKALU, OLANREWAJU, AROGUNDADE, & OLUWASEUN, ADELEKAN. (2012). STEADY STATE HEMOGLOBIN CONCENTRATION AND PACKED CELL VOLUME IN HOMOZYGOUS SICKLE CELL DISEASE PATIENTS IN LAGOS, NIGERIA. CASPIAN JOURNAL OF INTERNAL MEDICINE, 3(2 (10)), 405-409. SID. https://sid.ir/paper/323241/en

    Vancouver: Copy

    AKINBAMI AKINSEGUN, DOSUNMU ADEDOYIN, ADEDIRAN ADEWUMI, OSHINAIKE OLAJUMOKE, PHILLIP ADEBOLA, VINCENT OSUNKALU, OLANREWAJU AROGUNDADE, OLUWASEUN ADELEKAN. STEADY STATE HEMOGLOBIN CONCENTRATION AND PACKED CELL VOLUME IN HOMOZYGOUS SICKLE CELL DISEASE PATIENTS IN LAGOS, NIGERIA. CASPIAN JOURNAL OF INTERNAL MEDICINE[Internet]. 2012;3(2 (10)):405-409. Available from: https://sid.ir/paper/323241/en

    IEEE: Copy

    AKINSEGUN AKINBAMI, ADEDOYIN DOSUNMU, ADEWUMI ADEDIRAN, OLAJUMOKE OSHINAIKE, ADEBOLA PHILLIP, OSUNKALU VINCENT, AROGUNDADE OLANREWAJU, and ADELEKAN OLUWASEUN, “STEADY STATE HEMOGLOBIN CONCENTRATION AND PACKED CELL VOLUME IN HOMOZYGOUS SICKLE CELL DISEASE PATIENTS IN LAGOS, NIGERIA,” CASPIAN JOURNAL OF INTERNAL MEDICINE, vol. 3, no. 2 (10), pp. 405–409, 2012, [Online]. Available: https://sid.ir/paper/323241/en

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