Fecal calprotectin Level in patients with IBD and noninflammatory disease of colon: a study in Babol, Northern, Iran

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHARBATDARAN MAJID; Holaku Amin; KASHIFARD MEHRDAD; BIJANI ALI; Firozjahi Alireza; HOSSEINI AKRAM; SIADATI SEPIDEH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Caspian Journal of Internal Medicine Year:2018 | Volume:9 | Issue:1 Page(s): 60-64

Download Full-Text

View:

209

Download:

Cites:

Information Journal Paper

Title

Fecal calprotectin Level in patients with IBD and noninflammatory disease of colon: a study in Babol, Northern, Iran

Author(s)

Keywords

Fecal calprotectin level

Inflammatory bowel disease

Irritable bowel syndrome

Abstract

Background: Inflammatory bowel disease (IBD) is a chronic disease with a relapsing course of inflammation in the digestive system. Endoscopy and histopathology are the golden standard methods for detection and assessment of IBD. A distinct increase of Fecal calprotectin level can be a useful marker for the diagnosis of IBD. The aim of this study was to evaluate the Fecal calprotectin level in patients with IBD and without inflammatory diseases of the colon. Methods: Calprotectin levels of patients referred to the Ayatollah Rouhani Hospital of Babol, northern Iran with clinical symptoms of colon disease were evaluated. After a week, colonoscopy and biopsy were performed on all patients and they were divided into two groups. The first group included patients with confirmed IBD and the second group included patients with diseases other than IBD, patients with IBS and healthy persons. Then the measured Fecal calprotectin level was compared between the two groups before colonoscopy. Results: We observed correlation between calprotection in these two groups (p<0. 0001). 38 (86. 8%) patients in the case group and 5 (13. 2%) patients in the control group had positive fecal calprotectin test and 12 (23. 1%) patients in the case group and 40 (76. 9%) patients in the control group had negative results. Basad on ROC curve, the cutoff point of calprotectin was 127. 65 with 73% sensitivity and 89% specificity. The area under the curve was 0. 83 with 95% confidence interval, 0. 74-0. 91 (p<0. 0001). Conclusions: The results pointed to this fact that fecal calprotectin can be a noninvasive marker in differentiating IBD from IBS.

Cites

No record.

References

No record.

Cite

APA: Copy

SHARBATDARAN, MAJID, Holaku, Amin, KASHIFARD, MEHRDAD, BIJANI, ALI, Firozjahi, Alireza, HOSSEINI, AKRAM, & SIADATI, SEPIDEH. (2018). Fecal calprotectin Level in patients with IBD and noninflammatory disease of colon: a study in Babol, Northern, Iran. CASPIAN JOURNAL OF INTERNAL MEDICINE, 9(1), 60-64. SID. https://sid.ir/paper/323533/en

Vancouver: Copy

SHARBATDARAN MAJID, Holaku Amin, KASHIFARD MEHRDAD, BIJANI ALI, Firozjahi Alireza, HOSSEINI AKRAM, SIADATI SEPIDEH. Fecal calprotectin Level in patients with IBD and noninflammatory disease of colon: a study in Babol, Northern, Iran. CASPIAN JOURNAL OF INTERNAL MEDICINE[Internet]. 2018;9(1):60-64. Available from: https://sid.ir/paper/323533/en

IEEE: Copy

MAJID SHARBATDARAN, Amin Holaku, MEHRDAD KASHIFARD, ALI BIJANI, Alireza Firozjahi, AKRAM HOSSEINI, and SEPIDEH SIADATI, “Fecal calprotectin Level in patients with IBD and noninflammatory disease of colon: a study in Babol, Northern, Iran,” CASPIAN JOURNAL OF INTERNAL MEDICINE, vol. 9, no. 1, pp. 60–64, 2018, [Online]. Available: https://sid.ir/paper/323533/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops