مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Cites:

1

Information Journal Paper

Title

Resistance integrons; A mini review

Pages

  370-376

Abstract

 Integrons are a segment of dsDNA that play a major role in bacterial adaptation and evolution. These genetic determinants are known by the presence of three necessary apparatuses: an integrase (intI gene), Pc (a promoter) and attI (a recombination site). These elements are able to acquire gene cassettes, which can carry antibiotic resistance factors, via site-specific recombination mechanism. The most common types of resistance Integrons are class I (Tn402 derivatives), followed by class II and III. In recent years, the role of Integrons as an important factor in the transmission and spread of resistance factors has been considered. Therefore, the ongoing threats posed by Integrons require an understanding of their origins and evolutionary history. This review examines the functions and activities of Integrons. It shows how antibiotics use selected particular Integrons from the environmental pool, so that Integrons carrying resistance genes are now present in the majority of Gram-negative pathogens.

Cites

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    • Cite

    APA: Copy

    Akrami, Fariba, RAJABI KHOOZANI, MEHDI, & POURNAJAF, ABAZAR. (2019). Resistance integrons; A mini review. CASPIAN JOURNAL OF INTERNAL MEDICINE, 10(4), 370-376. SID. https://sid.ir/paper/323629/en

    Vancouver: Copy

    Akrami Fariba, RAJABI KHOOZANI MEHDI, POURNAJAF ABAZAR. Resistance integrons; A mini review. CASPIAN JOURNAL OF INTERNAL MEDICINE[Internet]. 2019;10(4):370-376. Available from: https://sid.ir/paper/323629/en

    IEEE: Copy

    Fariba Akrami, MEHDI RAJABI KHOOZANI, and ABAZAR POURNAJAF, “Resistance integrons; A mini review,” CASPIAN JOURNAL OF INTERNAL MEDICINE, vol. 10, no. 4, pp. 370–376, 2019, [Online]. Available: https://sid.ir/paper/323629/en

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