MICRODISSECTION TESE (MD-TESE) DOES NOT IMPROVE SPERM RETRIEVAL RATE BUT CONTRIBUTES TO FAVORABLE PREGNANCY RATE IN NON-OBSTRUCTIVE AZOOSPERMIC (NOA) PATIENTS

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HIBI HATSUKI; OHORI TADASHI; YAMADA YOSHIAKI; HONDA NOBUAKI; ITO CHIKAKO; SANO MIHO; HASHIBA YOSHIKI; ASADA YOSHIMASA

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Journal: Nephro-Urology Monthly Year:2010 | Volume:2 | Issue:3 Page(s): 455-461

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Title

MICRODISSECTION TESE (MD-TESE) DOES NOT IMPROVE SPERM RETRIEVAL RATE BUT CONTRIBUTES TO FAVORABLE PREGNANCY RATE IN NON-OBSTRUCTIVE AZOOSPERMIC (NOA) PATIENTS

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Keywords

NON-OBSTRUCTIVE AZOOSPERMIA

CONVENTIONAL TESE

MICRODISSECTION TESE

SPERM RECOVERY RATE

PREGNANCY RATE

Abstract

Background and Aims: Microdissection testicular sperm extraction TESE (MD-TESE), which can improve surgical sperm retrieval rate is widely applied in sperm retrieval surgery in non-obstructive azoospermic (NOA) patients. We assessed whether MD-TESE can improve sperm retrieval rate as well as Intracytoplasmic sperm injection (ICSI) results.Methods: A retrospective comparative study involving 86 NOA patients who underwent 6-8 conventional multiple TESE (C-TESE) procedures was conducted. Another 116 NOA patients underwent MD-TESE. CTESE and MD-TESE were employed for the bilateral testis via a median raphe incision under spinal or local anesthesia with spermatic block.Results: Motile sperm recovery was achieved in 26 (30.2%) and 30 (25.8%) patients with C-TESE and MDTESE, respectively. Collected sperm was cryopreserved. All couples in which motile sperm was recovered received ICSI utilizing frozen-thawed sperm samples. Overall PREGNANCY RATEs of the C-TESE and MD-TESE groups were 23% (6/26) and 40% (12/30), respectively. Abortion was not observed in either group and healthy deliveries resulted. Statistical differences in sperm recovery and PREGNANCY RATE were not evident between the groups (P=0.495, P=0.182, respectively). Moreover, no successful pre-operative predictors of sperm recovery were identified.Conclusions: These data demonstrated that MD-TESE does not improve SPERM RECOVERY RATE; however, MD-TESE contributes to favorable PREGNANCY RATE in NOA patients.

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APA: Copy

HIBI, HATSUKI, OHORI, TADASHI, YAMADA, YOSHIAKI, HONDA, NOBUAKI, ITO, CHIKAKO, SANO, MIHO, HASHIBA, YOSHIKI, & ASADA, YOSHIMASA. (2010). MICRODISSECTION TESE (MD-TESE) DOES NOT IMPROVE SPERM RETRIEVAL RATE BUT CONTRIBUTES TO FAVORABLE PREGNANCY RATE IN NON-OBSTRUCTIVE AZOOSPERMIC (NOA) PATIENTS. THE JOURNAL OF NEPHRO-UROLOGY MONTHLY, 2(3), 455-461. SID. https://sid.ir/paper/323717/en

Vancouver: Copy

HIBI HATSUKI, OHORI TADASHI, YAMADA YOSHIAKI, HONDA NOBUAKI, ITO CHIKAKO, SANO MIHO, HASHIBA YOSHIKI, ASADA YOSHIMASA. MICRODISSECTION TESE (MD-TESE) DOES NOT IMPROVE SPERM RETRIEVAL RATE BUT CONTRIBUTES TO FAVORABLE PREGNANCY RATE IN NON-OBSTRUCTIVE AZOOSPERMIC (NOA) PATIENTS. THE JOURNAL OF NEPHRO-UROLOGY MONTHLY[Internet]. 2010;2(3):455-461. Available from: https://sid.ir/paper/323717/en

IEEE: Copy

HATSUKI HIBI, TADASHI OHORI, YOSHIAKI YAMADA, NOBUAKI HONDA, CHIKAKO ITO, MIHO SANO, YOSHIKI HASHIBA, and YOSHIMASA ASADA, “MICRODISSECTION TESE (MD-TESE) DOES NOT IMPROVE SPERM RETRIEVAL RATE BUT CONTRIBUTES TO FAVORABLE PREGNANCY RATE IN NON-OBSTRUCTIVE AZOOSPERMIC (NOA) PATIENTS,” THE JOURNAL OF NEPHRO-UROLOGY MONTHLY, vol. 2, no. 3, pp. 455–461, 2010, [Online]. Available: https://sid.ir/paper/323717/en

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