LONGITUDINAL ASSESSMENT OF SERUM CREATININE LEVELS ON GRAFT SURVIVAL AFTER RENAL TRANSPLANTATION: JOINT MODELING APPROACH

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MARAGHI ELHAM; RAHIMI FOROUSHANI ABBAS; YOUNESPOUR SHIMA; ROSTAMI ZOHREH; EINOLLAHI BEHZAD; ESHRAGHIAN MOHAMMADREZA; AKHOOND MOHAMMAD REZA; MOHAMMAD KAZEM

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Journal: Nephro-Urology Monthly Year:2016 | Volume:8 | Issue:4 Page(s): 0-0

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Title

LONGITUDINAL ASSESSMENT OF SERUM CREATININE LEVELS ON GRAFT SURVIVAL AFTER RENAL TRANSPLANTATION: JOINT MODELING APPROACH

Author(s)

Keywords

END STAGE RENAL DISEASE (ESRD)

GRAFT FAILURE

JOINT MODELING

SERUM CREATININE

Abstract

Background: Chronic kidney disease (CKD) is a major public health problem. The eventual outcome of CKD is end-stage renal disease (ESRD). Early diagnosis and proper management play an important role in preventing CKD progression to ESRD. Dialysis and kidney transplantation are the only treatment options available for patients suffering from ESRD.Objectives: This study was designed to investigate the etiological role of recipient and donor characteristics on SERUM CREATININE changes within the follow-up period, GRAFT FAILURE risk, and the impact of longitudinal SERUM CREATININE levels on graft survival after renal transplantation.Patients and Methods: This study was carried out at the department of nephrology, Baqiyatallah hospital, Baqiyatallah University, Tehran, Iran, between April 2005 and December 2008. During that time period, 461 patients who had undergone renal transplantation were entered in the current study. Time to graft loss and SERUM CREATININE levels at each visit were the primary data gathered for the study. A JOINT MODELING of survival and longitudinal nonsurvival data was used to assess the association between the two processes and investigate the influential factors.Results: Median follow-up time was 6.80 months. A linear decreasing trend in SERUM CREATININE level over time was found (P< 0.001). The results showed a positive correlation between SERUM CREATININE levels and risk of GRAFT FAILURE (P<0.001).Conclusions: The major finding of this study is that one unit increase in SERUM CREATININE level suggests an increased risk of GRAFT FAILURE of up to four times.

Cites

Application of joint longitudinal and survival Model in the Study of Creatinine Correlation and Other Factors with the Survival of Kidney Transplantation

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APA: Copy

MARAGHI, ELHAM, RAHIMI FOROUSHANI, ABBAS, YOUNESPOUR, SHIMA, ROSTAMI, ZOHREH, EINOLLAHI, BEHZAD, ESHRAGHIAN, MOHAMMADREZA, AKHOOND, MOHAMMAD REZA, & MOHAMMAD, KAZEM. (2016). LONGITUDINAL ASSESSMENT OF SERUM CREATININE LEVELS ON GRAFT SURVIVAL AFTER RENAL TRANSPLANTATION: JOINT MODELING APPROACH. THE JOURNAL OF NEPHRO-UROLOGY MONTHLY, 8(4), 0-0. SID. https://sid.ir/paper/323800/en

Vancouver: Copy

MARAGHI ELHAM, RAHIMI FOROUSHANI ABBAS, YOUNESPOUR SHIMA, ROSTAMI ZOHREH, EINOLLAHI BEHZAD, ESHRAGHIAN MOHAMMADREZA, AKHOOND MOHAMMAD REZA, MOHAMMAD KAZEM. LONGITUDINAL ASSESSMENT OF SERUM CREATININE LEVELS ON GRAFT SURVIVAL AFTER RENAL TRANSPLANTATION: JOINT MODELING APPROACH. THE JOURNAL OF NEPHRO-UROLOGY MONTHLY[Internet]. 2016;8(4):0-0. Available from: https://sid.ir/paper/323800/en

IEEE: Copy

ELHAM MARAGHI, ABBAS RAHIMI FOROUSHANI, SHIMA YOUNESPOUR, ZOHREH ROSTAMI, BEHZAD EINOLLAHI, MOHAMMADREZA ESHRAGHIAN, MOHAMMAD REZA AKHOOND, and KAZEM MOHAMMAD, “LONGITUDINAL ASSESSMENT OF SERUM CREATININE LEVELS ON GRAFT SURVIVAL AFTER RENAL TRANSPLANTATION: JOINT MODELING APPROACH,” THE JOURNAL OF NEPHRO-UROLOGY MONTHLY, vol. 8, no. 4, pp. 0–0, 2016, [Online]. Available: https://sid.ir/paper/323800/en

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