RISK FACTORS FOR DETERIORATION OF RENAL FUNCTION AFTER CORONARY ARTERY BYPASS GRAFTING

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BAGHAEI R.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

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Journal: Iranian Journal of Toxicology Year:2010 | Volume:3 | Issue:5 Page(s): 21-21

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Title

RISK FACTORS FOR DETERIORATION OF RENAL FUNCTION AFTER CORONARY ARTERY BYPASS GRAFTING

Author(s)

BAGHAEI R.

Keywords

CORONARY ARTERY BYPASS GRAFTING

CABG

DATABASE

RENAL FUNCTION

Abstract

Objective: Various definitions of impairment of RENAL FUNCTION after CORONARY ARTERY BYPASS GRAFTING (CABG) are used in the literature. Depending on the definition, several risk factors are identified. We analysed our data to determine the risk factors for postoperative deterioration of the creatinine clearance of 10% or more.Methods: All patients undergoing isolated coronary surgery in a single centre between January 1998 and December 2007 are included. Clinical data, including demographics and renal risk factors, were prospectively collected in our DATABASE. The most recent preoperative serum creatinine level and the maximum serum creatinine level within the first week postoperatively were used to calculate the creatinine clearance. A deterioration of 10% or more was considered to be an endpoint for this study. The records of 144 infants less than 10 kg who underwent CPB for a variety of congenital cardiac procedures were reviewed. The GLU values (at multiple intervals during and after surgery), age, weight, CPB time, ultrafiltration volume, and risk adjustment for congenital heart surgery (RACHS-1) score were recorded. Univariate and multivariate linear and binary logistic regression were used to examine the dependence of the composite outcome mortality or postoperative infection, the mechanical ventilation time (VENT time), and the length of stay (LOS), on these variables.Results: In 10 098 out of a total of 10 626 patients, the preoperative as well as the postoperative creatinine clearance could be calculated. In 1053 patients, the deterioration of the creatinine clearance was 10% or more. We could identify the following risk factors: advanced age, diabetes, chronic obstructive pulmonary disease, peripheral vascular disease, emergency operation, previous cardiac surgery, low preoperative haemoglobin level, high preoperative C-reactive protein level, perioperative myocardial infarction, re-exploration and the number of blood transfusions.Conclusions: Risk factors for the deterioration of RENAL FUNCTION after revascularisation have been confirmed in this study. In addition, we found peripheral vascular disease, previous cardiac surgery, low preoperative haemoglobin, increased preoperative C-reactive protein level, perioperative myocardial infarction and the number of blood transfusions to be risk factors that have not been described earlier.

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APA: Copy

BAGHAEI, R.. (2010). RISK FACTORS FOR DETERIORATION OF RENAL FUNCTION AFTER CORONARY ARTERY BYPASS GRAFTING. IRANIAN JOURNAL OF TOXICOLOGY, 3(5), 21-21. SID. https://sid.ir/paper/324140/en

Vancouver: Copy

BAGHAEI R.. RISK FACTORS FOR DETERIORATION OF RENAL FUNCTION AFTER CORONARY ARTERY BYPASS GRAFTING. IRANIAN JOURNAL OF TOXICOLOGY[Internet]. 2010;3(5):21-21. Available from: https://sid.ir/paper/324140/en

IEEE: Copy

R. BAGHAEI, “RISK FACTORS FOR DETERIORATION OF RENAL FUNCTION AFTER CORONARY ARTERY BYPASS GRAFTING,” IRANIAN JOURNAL OF TOXICOLOGY, vol. 3, no. 5, pp. 21–21, 2010, [Online]. Available: https://sid.ir/paper/324140/en

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