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Information Journal Paper

Title

PREVALENCE AND COMPLICATIONS OF DRUG-INDUCED SEIZURES IN BAHARLOO HOSPITAL, TEHRAN, IRAN

Pages

  588-593

Keywords

Abstract

 Background: SEIZURE is a frequent and important finding in the field of clinical toxicology. Almost all poisons and DRUGs can produce SEIZURE. We have evaluated frequency and complications of DRUG-induced SEIZURE in present study.Methods: The present descriptive cross-sectional study was done on patients who were referred to Baharloo Hospital, Tehran, IRAN, that had developed SEIZURE before or after hospitalization following intoxication between 20 March 2010 and 20 March 2011. The exclusion criteria were a positive history of epilepsy, head trauma, or abnormal findings in EEG or brain CT scan.Results: Tramadol and tricyclic antidepressants were the most common causes of DRUG-induced SEIZURE (31.5% and 14.7% of the cases, respectively). Overall, 6 patients (4.2%) had developed persistent vegetative state in consequence of brain hypoxia, 16 patients (11.2%) had died due to complications of SEIZURE or the POISONING itself. Tramadol was the leading cause of DRUG-induced SEIZURE and its morbidity and mortality. Tonic-colonic SEIZURE was the most common type of DRUGinduced SEIZURE. SEIZURE had occurred once in 58% of the patients, twice in 37.1% of the patients, and had been revolutionized to status epilepticus in 4.9% of them. Among the 7 patients who had developed status epilepticus, 3 cases had died.Conclusion: Appropriate measures for treatment of SEIZURE and prevention of its complications should be taken when patients with DRUG POISONING are admitted into hospital, especially when the offending DRUG (s) has a higher likelihood to induce SEIZURE.

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    APA: Copy

    BEHNOUSH, BEHNAM, TAGHADOSINEJAD, FAKHREDIN, AREFI, MOHAMMAD, SHAHABI, MOHSEN, JAMALIAN, MOHAMMAD, & KAZEMIFAR, AMIR MOHAMMAD. (2012). PREVALENCE AND COMPLICATIONS OF DRUG-INDUCED SEIZURES IN BAHARLOO HOSPITAL, TEHRAN, IRAN. IRANIAN JOURNAL OF TOXICOLOGY, 6(16), 588-593. SID. https://sid.ir/paper/324262/en

    Vancouver: Copy

    BEHNOUSH BEHNAM, TAGHADOSINEJAD FAKHREDIN, AREFI MOHAMMAD, SHAHABI MOHSEN, JAMALIAN MOHAMMAD, KAZEMIFAR AMIR MOHAMMAD. PREVALENCE AND COMPLICATIONS OF DRUG-INDUCED SEIZURES IN BAHARLOO HOSPITAL, TEHRAN, IRAN. IRANIAN JOURNAL OF TOXICOLOGY[Internet]. 2012;6(16):588-593. Available from: https://sid.ir/paper/324262/en

    IEEE: Copy

    BEHNAM BEHNOUSH, FAKHREDIN TAGHADOSINEJAD, MOHAMMAD AREFI, MOHSEN SHAHABI, MOHAMMAD JAMALIAN, and AMIR MOHAMMAD KAZEMIFAR, “PREVALENCE AND COMPLICATIONS OF DRUG-INDUCED SEIZURES IN BAHARLOO HOSPITAL, TEHRAN, IRAN,” IRANIAN JOURNAL OF TOXICOLOGY, vol. 6, no. 16, pp. 588–593, 2012, [Online]. Available: https://sid.ir/paper/324262/en

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