INFLUENCE OF AGE AND GENDER ON ASSOCIATION BETWEEN -765G>C COX-2 GENETIC POLYMORPHISM AND GASTRIC ADENOCARCINOMA RISK: A CASE-CONTROL STUDY IN IRAN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ROSTAMI MASUMEH; KADIVAR MEHDI; AZNAB MOZAFFAR; ABACHI MINA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Gastroenterology and Hepatology From Bed to Bench Year:2012 | Volume:5 | Issue:1 Page(s): 29-34

Download Full-Text

View:

188

Download:

Cites:

Information Journal Paper

Title

INFLUENCE OF AGE AND GENDER ON ASSOCIATION BETWEEN -765G>C COX-2 GENETIC POLYMORPHISM AND GASTRIC ADENOCARCINOMA RISK: A CASE-CONTROL STUDY IN IRAN

Author(s)

ROSTAMI MASUMEH | KADIVAR MEHDI | AZNAB MOZAFFAR | ABACHI MINA | Issue Writer Certificate

Keywords

GASTRIC ADENOCARCINOMA

COX-2 POLYMORPHISM

PCR-RFLP

Abstract

Aim: The purpose of this study was to investigate the possible influence of age and gender on association between -765G>C COX-2 genetic polymorphism and GASTRIC ADENOCARCINOMA risk in Iranian patients.Background: The promoter polymorphism of COX-2 gene -765G>C has been described to play an important role in many cancers such as gastric cancer.Patients and methods: We carried out single-nucleotide polymorphism analysis in Iranian samples including 91 patients and 91 control normal using PCR- RFLP technique.Results: Statistical analysis revealed no significant association between GG, GC and CC genotypes and risk of GASTRIC ADENOCARCINOMA. However differences were considered significant (P=0.043) for female subjects with C carrier genotypes (GC and CC) and GASTRIC ADENOCARCINOMA when compared with male patients (P=0.645) and control groups (P=0.653). Also, there was a statistically significant difference between increasing of age and susceptibility for GASTRIC ADENOCARCINOMA (Odd Ratio=1.125, 95% CI=1.089-1.162).Conclusion: These results suggested that Iranian C carrier females can be more susceptible for GASTRIC ADENOCARCINOMA in comparison with control group. Also increasing of age should be considered as a risk factor for this disease.

Cites

No record.

References

No record.

Cite

APA: Copy

ROSTAMI, MASUMEH, KADIVAR, MEHDI, AZNAB, MOZAFFAR, & ABACHI, MINA. (2012). INFLUENCE OF AGE AND GENDER ON ASSOCIATION BETWEEN -765G>C COX-2 GENETIC POLYMORPHISM AND GASTRIC ADENOCARCINOMA RISK: A CASE-CONTROL STUDY IN IRAN. GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH, 5(1), 29-34. SID. https://sid.ir/paper/324563/en

Vancouver: Copy

ROSTAMI MASUMEH, KADIVAR MEHDI, AZNAB MOZAFFAR, ABACHI MINA. INFLUENCE OF AGE AND GENDER ON ASSOCIATION BETWEEN -765G>C COX-2 GENETIC POLYMORPHISM AND GASTRIC ADENOCARCINOMA RISK: A CASE-CONTROL STUDY IN IRAN. GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH[Internet]. 2012;5(1):29-34. Available from: https://sid.ir/paper/324563/en

IEEE: Copy

MASUMEH ROSTAMI, MEHDI KADIVAR, MOZAFFAR AZNAB, and MINA ABACHI, “INFLUENCE OF AGE AND GENDER ON ASSOCIATION BETWEEN -765G>C COX-2 GENETIC POLYMORPHISM AND GASTRIC ADENOCARCINOMA RISK: A CASE-CONTROL STUDY IN IRAN,” GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH, vol. 5, no. 1, pp. 29–34, 2012, [Online]. Available: https://sid.ir/paper/324563/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops