PREGNANCY WITH AUTOIMMUNE HEPATITIS (BRIEF REPORT)

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BRAGA ANTONIO COSTA; VASCONCELOS CARLOS; BRAGA JORGE

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Journal Paper

Paper Information

Journal: Gastroenterology and Hepatology From Bed to Bench Year:2016 | Volume:9 | Issue:3 Page(s): 220-224

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Information Journal Paper

Title

PREGNANCY WITH AUTOIMMUNE HEPATITIS (BRIEF REPORT)

Author(s)

BRAGA ANTONIO COSTA | VASCONCELOS CARLOS | BRAGA JORGE | Issue Writer Certificate

Keywords

HIGH-RISK PREGNANCY

LIVER DISORDER AND PREGNANCY

AZATHIOPRINE

Abstract

Aim: The aim of this study was to review our experience with gestations in autoimmune hepatitis patients.Background: There are only limited data describing pregnancy in patients with autoimmune hepatitis. Patients and methods: Retrospective analysis of pregnancies with autoimmune hepatitis followed in Centro Hospitalar do Porto, Portugal in the last ten years.Results: We reported nine pregnancies in seven patients with autoimmune hepatitis. Two patients had documented liver cirrhosis prior to the pregnancy. In this study, 66.7% of patients were treated with AZATHIOPRINE and 88.9% with prednisolone. Clinical improvements were observed in 11.1% of pregnancies and 22.2% exacerbations were diagnosed. There were six live births and two preterm deliveries (preterm delivery rate of 33%). We also report three first trimester miscarriages (early gestation miscarriage rate of 33%). There were no neonatal or maternal deaths.Conclusion: The favorable obstetric outcome is a realistic expectation in patients with autoimmune hepatitis. Tight monitoring and control of asymptomatic and unpredictable exacerbations, which are unrelated to the severity of the underlying disease, are essential to the prognosis of the current pregnancy.

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APA: Copy

BRAGA, ANTONIO COSTA, VASCONCELOS, CARLOS, & BRAGA, JORGE. (2016). PREGNANCY WITH AUTOIMMUNE HEPATITIS (BRIEF REPORT). GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH, 9(3), 220-224. SID. https://sid.ir/paper/324660/en

Vancouver: Copy

BRAGA ANTONIO COSTA, VASCONCELOS CARLOS, BRAGA JORGE. PREGNANCY WITH AUTOIMMUNE HEPATITIS (BRIEF REPORT). GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH[Internet]. 2016;9(3):220-224. Available from: https://sid.ir/paper/324660/en

IEEE: Copy

ANTONIO COSTA BRAGA, CARLOS VASCONCELOS, and JORGE BRAGA, “PREGNANCY WITH AUTOIMMUNE HEPATITIS (BRIEF REPORT),” GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH, vol. 9, no. 3, pp. 220–224, 2016, [Online]. Available: https://sid.ir/paper/324660/en

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