COMPARISON OF LOW-LEVEL LASER THERAPY PLUS TOPICAL CORTICOSTEROID THERAPY WITH TOPICAL CORTICOSTEROID THERAPY ALONE IN TREATMENT OF RECURRENT APHTHOUS STOMATITIS

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SHIRANI AMIR MANSOUR; HONARVAR PARISA

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Journal Paper

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Journal: JOURNAL OF LASERS IN MEDICAL SCIENCES Year:2018 | Volume:9 | Issue:SUPPL A (9TH WORLD CONGRESS OF SOLA) Page(s): 35-35

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Title

COMPARISON OF LOW-LEVEL LASER THERAPY PLUS TOPICAL CORTICOSTEROID THERAPY WITH TOPICAL CORTICOSTEROID THERAPY ALONE IN TREATMENT OF RECURRENT APHTHOUS STOMATITIS

Author(s)

SHIRANI AMIR MANSOUR | HONARVAR PARISA

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Abstract

Background: Recurring aphthous stomatitis are common and painful ulcers of the mouth. Many different treatment methods have been used to reduce pain intensity and remission time. Common treatment consists of topical corticosteroid with anesthetic and lining material. In some studies, the efficacy of low-level laser therapy compared with topical corticosteroid and laser placebo were studied. In this research, for the first time, low-level laser therapy plus topical corticosteroid was compared with topical corticosteroid alone for treatment of recurrent aphthous stomatitis.Methods: In this single-blinded clinical trial, 30 patients with early (first 48 hours) minor aphthous ulcers based on the inclusion and exclusion criteria and ethical issues, were randomly distributed in two 15-person groups; in one group of low-level laser plus topical corticosteroid and in the other group topical corticosteroid alone were used. All the patients received standard treatment, diphenhydramine syrup as mouthwash for one minute before food consumption and topical corticosteroid used as a combination of 3 betamethazone ampoules dissolved in magnesium syrup 3 times per day after meal and one-minute gargling. This treatment was continued up to ulcers healing. For the laser group, low-level laser therapy was done using diode 660 nm (LT-R, Behsaz Gostar, Iran, class IIIB) 4 J/cm2, 100 mW, 0 Hz and 40 seconds in 2 sessions (first and third day), perpendicular to the lesion and nearly in contact mode. Both groups were examined every day and remission time (clinical disappearing of lesions) and pain intensity according to visual analogue scale (VAS) were compared. Data were analyzed using SPSS 20 software package and statistical independentt test and Mann-Whitney.Results: Mean of VAS, on the fourth day of examination in the topical corticosteroid plus low-level laser group was significantly lower than in the topical corticosteroid alone group (P=0.04). The average lesion size at the fourth day of examination in the low-level laser plus topical corticosteroid group was significantly lower than in the topical corticosteroid alone group (P=0.02).The difference in pain-free (P<0.001) and complete clinical healing (P<0.001) in the laser group was significantly lower than the standard treatment group.Conclusion: The results of the research showed that low-level laser plus topical corticosteroid is significantly more effective in reducing pain intensity and recovery from recurrent aphthous stomatitis in comparison with topical corticosteroid alone.

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APA: Copy

SHIRANI, AMIR MANSOUR, & HONARVAR, PARISA. (2018). COMPARISON OF LOW-LEVEL LASER THERAPY PLUS TOPICAL CORTICOSTEROID THERAPY WITH TOPICAL CORTICOSTEROID THERAPY ALONE IN TREATMENT OF RECURRENT APHTHOUS STOMATITIS. JOURNAL OF LASERS IN MEDICAL SCIENCES, 9(SUPPL A (9TH WORLD CONGRESS OF SOLA)), 35-35. SID. https://sid.ir/paper/326074/en

Vancouver: Copy

SHIRANI AMIR MANSOUR, HONARVAR PARISA. COMPARISON OF LOW-LEVEL LASER THERAPY PLUS TOPICAL CORTICOSTEROID THERAPY WITH TOPICAL CORTICOSTEROID THERAPY ALONE IN TREATMENT OF RECURRENT APHTHOUS STOMATITIS. JOURNAL OF LASERS IN MEDICAL SCIENCES[Internet]. 2018;9(SUPPL A (9TH WORLD CONGRESS OF SOLA)):35-35. Available from: https://sid.ir/paper/326074/en

IEEE: Copy

AMIR MANSOUR SHIRANI, and PARISA HONARVAR, “COMPARISON OF LOW-LEVEL LASER THERAPY PLUS TOPICAL CORTICOSTEROID THERAPY WITH TOPICAL CORTICOSTEROID THERAPY ALONE IN TREATMENT OF RECURRENT APHTHOUS STOMATITIS,” JOURNAL OF LASERS IN MEDICAL SCIENCES, vol. 9, no. SUPPL A (9TH WORLD CONGRESS OF SOLA), pp. 35–35, 2018, [Online]. Available: https://sid.ir/paper/326074/en

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