EFFECTS OF CO2 LASER THERAPY ON RESISTANT ORAL LICHEN PLANUS

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REZAEI FATEMEH; DEHGHANI NIMA

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Journal: JOURNAL OF LASERS IN MEDICAL SCIENCES Year:2018 | Volume:9 | Issue:SUPPL A (9TH WORLD CONGRESS OF SOLA) Page(s): 23-23

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Title

EFFECTS OF CO2 LASER THERAPY ON RESISTANT ORAL LICHEN PLANUS

Author(s)

REZAEI FATEMEH | DEHGHANI NIMA

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Abstract

Background: Oral lichen planus (OLP) is a chronic mucocutaneous disease with no specifically identified etiology and pathogenesis. Different causes are proposed to be related to OLP, including stress, genetics, systemic diseases, medicines, dental restorative materials, and viruses. Some of these lesions are resistant to the typical corticosteroid therapy. This study was aimed at evaluating the therapeutic effects of CO2 laser therapy on OLP.Methods: In the present clinical experiment, 50 patients with a histopathologic diagnosis of OLP and resistance to local corticosteroids were studied. The patients were divided into 2 groups: control group (treated with local corticosteroids) and experimental group (treated with CO2 laser). Before the study, 15 days, 1, 3, and 6 months after treatment, the pain level was measured with visual analogous scale (VAS) and the size of the lesion was determined. Efficiency index (EI) was utilized to evaluate the changes in lesion size. The collected data were analyzed using Freedman and Mann-Whitney tests through SPSS 18.0 (P<0.05).Results: At the beginning of the study, there was no significant difference between the groups [(mean VAS: 5.84±2.44 vs. 6.2±2.47, P=0.823) and (lesion diameter: 2.48±1.47 vs. 2.34±1.15, P=0.944)]. After treatment with CO2 laser, pain level in the experimental group was 1.84±3.24 compared to the control group (5.12±3.02) (P<0.001) and the size of the lesion was 0.73±1.19 versus 2.02±1.27 (P<0.001). Laser therapy efficiency index was higher than that of local treatment with corticosteroids (P<0.001). In recent years, laser irradiation in treating mucocutaneous lesions has shown positive results. The present study showed that laser therapy caused a reduction in lesion size during a 6-month period. Similar findings were reported by Pakfetrat et al who observed a significant reduction of pain and burning following CO2 therapy during 3 months. The mechanism behind lesion improvement in laser treatment is related to the laser power. In previous studies, low-power lasers with low range and different powers were reported to have 25%-85% improvement, while in this study with a 2 W power, 84% improvement was recorded.Conclusion: Radiation of CO2 laser on OLP lesions that are resistant to local corticosteroids can reduce pain level and lesion size more than corticosteroid therapy.

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APA: Copy

REZAEI, FATEMEH, & DEHGHANI, NIMA. (2018). EFFECTS OF CO2 LASER THERAPY ON RESISTANT ORAL LICHEN PLANUS. JOURNAL OF LASERS IN MEDICAL SCIENCES, 9(SUPPL A (9TH WORLD CONGRESS OF SOLA)), 23-23. SID. https://sid.ir/paper/326089/en

Vancouver: Copy

REZAEI FATEMEH, DEHGHANI NIMA. EFFECTS OF CO2 LASER THERAPY ON RESISTANT ORAL LICHEN PLANUS. JOURNAL OF LASERS IN MEDICAL SCIENCES[Internet]. 2018;9(SUPPL A (9TH WORLD CONGRESS OF SOLA)):23-23. Available from: https://sid.ir/paper/326089/en

IEEE: Copy

FATEMEH REZAEI, and NIMA DEHGHANI, “EFFECTS OF CO2 LASER THERAPY ON RESISTANT ORAL LICHEN PLANUS,” JOURNAL OF LASERS IN MEDICAL SCIENCES, vol. 9, no. SUPPL A (9TH WORLD CONGRESS OF SOLA), pp. 23–23, 2018, [Online]. Available: https://sid.ir/paper/326089/en

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