مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Cites:

1

Information Journal Paper

Title

ANTIFUNGAL ACTIVITY OF ESSENTIAL OILS FROM IRANIAN PLANTS AGAINST FLUCONAZOLE-RESISTANT AND FLUCONAZOLE-SUSCEPTIBLE CANDIDA ALBICANS

Pages

  215-222

Abstract

 Objective: The purpose of this study was to assay the antifungal activity of selected ESSENTIAL OILS obtained from plants against both fluconazole (FLU)-resistant and FLU-susceptible C. albicans strains isolated from HIV positive patients with oropharyngeal candidiasis (OPC).Materials and Methods: The ESSENTIAL OILS were obtained by hydrodistillation method from Myrtus communis (My. communis), Zingiber officinale roscoe (Z. officinale roscoe), Matricaria chamomilla (Ma. chamomilla), Trachyspermum ammi (T. ammi) and ORIGANUM VULGARE (O. vulgare). The susceptibility test was based on the M27-A2 methodology. The chemical compositions of the ESSENTIAL OILS were obtained by gas chromatography- mass spectroscopy (GC-MS).Results: In GC-MS analysis, thymol (63.40%), linalool (42%), a-pinene (27.87%), a-pinene (22.10%), and zingiberene (31.79%) were found to be the major components of T. ammi, O. vulgare, My. communis, Ma. chamomilla and Z. officinale roscoe, respectively. The results showed that ESSENTIAL OILS have different levels of antifungal activity. O. vulgare and T. ammi ESSENTIAL OILS were found to be the most efficient (P<0.05). The main finding was that the susceptibilities of FLU-resistant C. albicans to ESSENTIAL OILS were higher than those of the FLU-susceptible yeasts.Conclusion: Results of this study indicated that the oils from medicinal plants could be used as potential anti- FLU-resistant C. albicans agents.

Cites

References

Cite

APA: Copy

SHARIFZADEH, AGHIL, & SHOKRI, HOJJATOLLAH. (2016). ANTIFUNGAL ACTIVITY OF ESSENTIAL OILS FROM IRANIAN PLANTS AGAINST FLUCONAZOLE-RESISTANT AND FLUCONAZOLE-SUSCEPTIBLE CANDIDA ALBICANS. AVICENNA JOURNAL OF PHYTOMEDICINE (AJP), 6(2), 215-222. SID. https://sid.ir/paper/326337/en

Vancouver: Copy

SHARIFZADEH AGHIL, SHOKRI HOJJATOLLAH. ANTIFUNGAL ACTIVITY OF ESSENTIAL OILS FROM IRANIAN PLANTS AGAINST FLUCONAZOLE-RESISTANT AND FLUCONAZOLE-SUSCEPTIBLE CANDIDA ALBICANS. AVICENNA JOURNAL OF PHYTOMEDICINE (AJP)[Internet]. 2016;6(2):215-222. Available from: https://sid.ir/paper/326337/en

IEEE: Copy

AGHIL SHARIFZADEH, and HOJJATOLLAH SHOKRI, “ANTIFUNGAL ACTIVITY OF ESSENTIAL OILS FROM IRANIAN PLANTS AGAINST FLUCONAZOLE-RESISTANT AND FLUCONAZOLE-SUSCEPTIBLE CANDIDA ALBICANS,” AVICENNA JOURNAL OF PHYTOMEDICINE (AJP), vol. 6, no. 2, pp. 215–222, 2016, [Online]. Available: https://sid.ir/paper/326337/en

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