مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

Effect of chamomile on chemotherapy-induced neutropenia in pediatric leukemia patients: A randomized triple-blind placebo-controlled clinical trial

Pages

  58-69

Abstract

 Objective: Chemotherapy-induced Neutropenia is one of the main side effects of acute lymphoblastic Leukemia (ALL) treatment. In this trial, we evaluated the efficacy of Chamomile in management of Neutropenia. Materials and Methods: This randomized triple-blind placebo-controlled clinical trial was carried out in 2-18-year-old children with ALL. Participants in each group daily received 2. 5 ml of either Chamomile syrup or placebo syrup for a period of 30 days. Participants’ white blood cell (WBC), and absolute neutrophil count (ANC), as well as their quality of life were evaluated. Results: The study was completed with a total of 40 patients. An increasing trend of ANC was observed in the treatment group despite the decreasing trend in placebo group, which was statistically significant between the two groups (P Interaction=0. 019, 95% confidence intervals=15. 076– 171. 324). No serious side effects were reported. Conclusion: Using Chamomile syrup as a complementary therapy in children with Leukemia could improve their immunity (as it increased WBC) by minimizing Chemotherapy-induced Neutropenia.

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    APA: Copy

    DANESHFARD, BABAK, SHAHRIARI, MAHDI, Heiran, Alireza, NIMROUZI, MAJID, & YARMOHAMMADI, HASSAN. (2020). Effect of chamomile on chemotherapy-induced neutropenia in pediatric leukemia patients: A randomized triple-blind placebo-controlled clinical trial. AVICENNA JOURNAL OF PHYTOMEDICINE (AJP), 10(1), 58-69. SID. https://sid.ir/paper/326476/en

    Vancouver: Copy

    DANESHFARD BABAK, SHAHRIARI MAHDI, Heiran Alireza, NIMROUZI MAJID, YARMOHAMMADI HASSAN. Effect of chamomile on chemotherapy-induced neutropenia in pediatric leukemia patients: A randomized triple-blind placebo-controlled clinical trial. AVICENNA JOURNAL OF PHYTOMEDICINE (AJP)[Internet]. 2020;10(1):58-69. Available from: https://sid.ir/paper/326476/en

    IEEE: Copy

    BABAK DANESHFARD, MAHDI SHAHRIARI, Alireza Heiran, MAJID NIMROUZI, and HASSAN YARMOHAMMADI, “Effect of chamomile on chemotherapy-induced neutropenia in pediatric leukemia patients: A randomized triple-blind placebo-controlled clinical trial,” AVICENNA JOURNAL OF PHYTOMEDICINE (AJP), vol. 10, no. 1, pp. 58–69, 2020, [Online]. Available: https://sid.ir/paper/326476/en

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