In vitro antibacterial activity of curcumin-meropenem combination against extensively drug-resistant (XDR) bacteria isolated from burn wound infections (Short Communication)

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Yasbolaghi Sharahi Javad; Aliakbar Ahovan Zahra; TAGHIZADEH MALEKI DONYA; Riahi Rad Zahra; Riahi Rad Zohreh; GOUDARZI MEHDI; SHARIATI AREF; Bostanghadiri Narjes; ABBASI ELHAM; HASHEMI ALI

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Avicenna Journal of Phytomedicine Year:2020 | Volume:10 | Issue:1 Page(s): 3-10

Download Full-Text

View:

241

Download:

150

Cites:

Information Journal Paper

Title

In vitro antibacterial activity of curcumin-meropenem combination against extensively drug-resistant (XDR) bacteria isolated from burn wound infections (Short Communication)

Author(s)

Keywords

Curcumin

Meropenem

Extensively drug-resistant (XDR)

Antibacterial

Wound Infections

Abstract

Objective: Burn wound infection is a severe complication of thermal injury. Patients with severe burn injuries need urgent care to diminish complications after severe burns. Wound Infections are commonly considered one of the most serious burn complications, particularly those that are caused by extensively drug-resistant (XDR) bacteria with few therapeutic choices. The objective of this study was to determine in vitro activity of Meropenem and Curcumin, alone and in combination, against antibiotic-susceptible Gram-positive, and antibiotic-resistant and antibiotic susceptible gram-negative bacteria isolated from burn Wound Infections. Materials and Methods: The antimicrobial activity of Meropenem and Curcumin was investigated alone and in combination, against antibiotic-susceptible and antibiotic-resistant bacterial (XDR) strains isolated from burn patients. In addition, the cytotoxic effect of Curcumin on human’ s epithelial cell lines, was determined. Results: In this study, minimum inhibitory concentrations of Meropenem decreased considerably in the presence of Curcumin (2-to 16-fold reductions), with synergy observed. Curcumin exerted no cytotoxic effect at concentrations 256-512 μ g/ml on human epithelial cell lines. Conclusion: We suggest that Curcumin-antibiotic combinations may provide an alternative approach for treating infections with multidrug-resistant (MDR) and extensively drug-resistant (XDR) bacteria.

Cites

No record.

References

Cite

APA: Copy

Yasbolaghi Sharahi, Javad, Aliakbar Ahovan, Zahra, TAGHIZADEH MALEKI, DONYA, Riahi Rad, Zahra, Riahi Rad, Zohreh, GOUDARZI, MEHDI, SHARIATI, AREF, Bostanghadiri, Narjes, ABBASI, ELHAM, & HASHEMI, ALI. (2020). In vitro antibacterial activity of curcumin-meropenem combination against extensively drug-resistant (XDR) bacteria isolated from burn wound infections (Short Communication). AVICENNA JOURNAL OF PHYTOMEDICINE (AJP), 10(1), 3-10. SID. https://sid.ir/paper/326478/en

Vancouver: Copy

Yasbolaghi Sharahi Javad, Aliakbar Ahovan Zahra, TAGHIZADEH MALEKI DONYA, Riahi Rad Zahra, Riahi Rad Zohreh, GOUDARZI MEHDI, SHARIATI AREF, Bostanghadiri Narjes, ABBASI ELHAM, HASHEMI ALI. In vitro antibacterial activity of curcumin-meropenem combination against extensively drug-resistant (XDR) bacteria isolated from burn wound infections (Short Communication). AVICENNA JOURNAL OF PHYTOMEDICINE (AJP)[Internet]. 2020;10(1):3-10. Available from: https://sid.ir/paper/326478/en

IEEE: Copy

Javad Yasbolaghi Sharahi, Zahra Aliakbar Ahovan, DONYA TAGHIZADEH MALEKI, Zahra Riahi Rad, Zohreh Riahi Rad, MEHDI GOUDARZI, AREF SHARIATI, Narjes Bostanghadiri, ELHAM ABBASI, and ALI HASHEMI, “In vitro antibacterial activity of curcumin-meropenem combination against extensively drug-resistant (XDR) bacteria isolated from burn wound infections (Short Communication),” AVICENNA JOURNAL OF PHYTOMEDICINE (AJP), vol. 10, no. 1, pp. 3–10, 2020, [Online]. Available: https://sid.ir/paper/326478/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops