PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY AFTER THREE CONSECUTIVE LIVER TRANSPLANTATIONS (CASE REPORT)

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OZDEMIR F.; INCE VOLKAN; BASKIRAN A.; OZDEMIR Z.; BAYINDIR Y.; OTLU B.; YILMAZ S.

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Journal Paper

Paper Information

Journal: International Journal of Organ Transplantation Medicine Year:2015 | Volume:6 | Issue:3 Page(s): 126-130

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Information Journal Paper

Title

PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY AFTER THREE CONSECUTIVE LIVER TRANSPLANTATIONS (CASE REPORT)

Author(s)

Keywords

LIVER TRANSPLANTATION

LEUKOENCEPHALOPATHY

PROGRESSIVE MULTIFOCAL

JC VIRUS

IMMUNOCOMPROMISED HOST

VIRAL LOAD

Abstract

Progressive multifocal LEUKOENCEPHALOPATHY (PML) is a lytic infection of the central nervous system caused by the reactivation of John Cunningham Virus (JCV) in severely immunosuppressed patients. Occurrence of PML after solid organ transplantations, especially after LIVER TRANSPLANTATION, is rare. If a patient has poor prognostic factors such as atypical radiological involvements or high VIRAL LOAD in cerebrospinal fluid (CSF), overall survival rates could be poor. Herein, we report on a patients who underwent LIVER TRANSPLANTATION three times and developed PML with unexpected radiological findings; he was also positive for JCV DNA with a high VIRAL LOAD. Although there are limited data about efficacy of cytarabine against JCV, it was given to the patient for five days. Despite the initiation of cytarabine and complete cessation of the immunosuppressive therapy, we lost the patient, unfortunately.

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APA: Copy

OZDEMIR, F., INCE, VOLKAN, BASKIRAN, A., OZDEMIR, Z., BAYINDIR, Y., OTLU, B., & YILMAZ, S.. (2015). PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY AFTER THREE CONSECUTIVE LIVER TRANSPLANTATIONS (CASE REPORT). INTERNATIONAL JOURNAL OF ORGAN TRANSPLANTATION MEDICINE, 6(3), 126-130. SID. https://sid.ir/paper/327535/en

Vancouver: Copy

OZDEMIR F., INCE VOLKAN, BASKIRAN A., OZDEMIR Z., BAYINDIR Y., OTLU B., YILMAZ S.. PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY AFTER THREE CONSECUTIVE LIVER TRANSPLANTATIONS (CASE REPORT). INTERNATIONAL JOURNAL OF ORGAN TRANSPLANTATION MEDICINE[Internet]. 2015;6(3):126-130. Available from: https://sid.ir/paper/327535/en

IEEE: Copy

F. OZDEMIR, VOLKAN INCE, A. BASKIRAN, Z. OZDEMIR, Y. BAYINDIR, B. OTLU, and S. YILMAZ, “PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY AFTER THREE CONSECUTIVE LIVER TRANSPLANTATIONS (CASE REPORT),” INTERNATIONAL JOURNAL OF ORGAN TRANSPLANTATION MEDICINE, vol. 6, no. 3, pp. 126–130, 2015, [Online]. Available: https://sid.ir/paper/327535/en

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