HEMODYNAMIC EFFECTS OF THREE DOSES OF DIHYDROERGOTAMINE DURING SPINAL ANESTHESIA

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SAHM ALDINI M.A.; NIKANDISH R.; KHADEMI S.

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Journal: KOWSAR MEDICAL JOURNAL Year:2006 | Volume:11 | Issue:1 Page(s): 69-74

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Title

HEMODYNAMIC EFFECTS OF THREE DOSES OF DIHYDROERGOTAMINE DURING SPINAL ANESTHESIA

Author(s)

SAHM ALDINI M.A. | NIKANDISH R. | KHADEMI S. | Issue Writer Certificate

Keywords

SPINAL ANESTHESIAQ3

DIHYDROERGOTAMINEQ3

HYPOTENSIONQ3

Abstract

Objective: This study was done to survey hemodynamic effects of DIHYDROERGOTAMINE (DHE) during SPINAL ANESTHESIA and detection of the optimal IV dose.Material and Methods: In this clinical study the hemodynamic effects of three dose of DHE (5, 10,15mcg/kg) were evaluated in 90 patients who were schedule for elective inguinal herniorraphy under SPINAL ANESTHESIA. Patients were randomly divided in 3 groups. All were in class land 2 ASA and aged 40-60 yrs. Non-invasive diastolic and systolic blood pressure and heart rate of patients, before and after SPINAL ANESTHESIA and after IV injection of DHE every 3 minutes were recorded. During this period the patients did not received IV fluid.Results: All three dose of DHE treated diastolic and systolic HYPOTENSION due to SPINAL ANESTHESIA, (p<0.0001). A dose of 5mcg/kg increased blood pressure near to that before SPINAL ANESTHESIA. A dose of 10 mcg/kg increased diastolic and systolic pressure up to 7% and 8% baseline respectively. A dose of 15mcg/kg increased diastolic and systolic pressure up to 13% and 15% baseline respectively (p<0.0001).Conclusion: According to the above findings DHE is effective for treatment of HYPOTENSION during the SPINAL ANESTHESIA and this effect is not dependent on Iv fluid administrationa dose of 5-10 mcg/kg is suggested.

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APA: Copy

SAHM ALDINI, M.A., NIKANDISH, R., & KHADEMI, S.. (2006). HEMODYNAMIC EFFECTS OF THREE DOSES OF DIHYDROERGOTAMINE DURING SPINAL ANESTHESIA. KOWSAR MEDICAL JOURNAL, 11(1), 69-74. SID. https://sid.ir/paper/32782/en

Vancouver: Copy

SAHM ALDINI M.A., NIKANDISH R., KHADEMI S.. HEMODYNAMIC EFFECTS OF THREE DOSES OF DIHYDROERGOTAMINE DURING SPINAL ANESTHESIA. KOWSAR MEDICAL JOURNAL[Internet]. 2006;11(1):69-74. Available from: https://sid.ir/paper/32782/en

IEEE: Copy

M.A. SAHM ALDINI, R. NIKANDISH, and S. KHADEMI, “HEMODYNAMIC EFFECTS OF THREE DOSES OF DIHYDROERGOTAMINE DURING SPINAL ANESTHESIA,” KOWSAR MEDICAL JOURNAL, vol. 11, no. 1, pp. 69–74, 2006, [Online]. Available: https://sid.ir/paper/32782/en

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