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Information Journal Paper

Title

USE OF REMIFENTANIL AND ALFENTANIL IN ENDOTRACHEAL INTUBATION: A COMPARATIVE STUDY

Pages

  61-65

Abstract

 Background: Opioids, such as ALFENTANIL, are used to facilitate ENDOTRACHEAL INTUBATION without the use of neuromuscular blocking agents in patients undergoing elective surgery.Objectives: The goal of this study was to evaluate the ENDOTRACHEAL INTUBATION conditions when REMIFENTANIL or ALFENTANIL was used with PROPOFOL without the application of neuromuscular blocking agents.Patients and Methods: One hundred American Society of Anesthesiologists (ASA) grade I patients scheduled for elective surgery were enrolled in this prospective, randomized, triple-blinded study. The patients were randomized to group A (ALFENTANIL) or R (remifentanil). In group A, ALFENTANIL (50 mcg/kg) was intravenously injected over 10 seconds, and after 45 seconds or at the occurrence of apnea, PROPOFOL (2 mg/kg) was intravenously injected over 5 seconds. Thirty seconds after the administration of PROPOFOL, laryngoscopy and ENDOTRACHEAL INTUBATION were attempted. In group R, REMIFENTANIL (5 mcg/kg) was administered instead of ALFENTANIL. Intubation conditions, including ease of laryngoscopy, patency of the vocal cords, jaw relaxation, limb movement (1-4 score), and also, demographic data were evaluated.Results: There were no demographic data differerences between groups (age, weight, and sex). Further, laryngoscopy, jaw relaxation, and limb movement scores were similar in the R and A groups and there were no significant differences, but vocal cords were significantly more patent in group R than those in group A (P=0.028).Conclusions: The results of this study showed that REMIFENTANIL, similar to ALFENTANIL, provided excellent conditions for ENDOTRACHEAL INTUBATION when used with PROPOFOL for the induction of anesthesia; however, REMIFENTANIL improved the patency of the vocal cords to a greater extent than ALFENTANIL.

Cites

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    • Cite

    APA: Copy

    IMANI, FARNAD, ALEBOUYEH, MAHMOUD REZA, TAGHIPOUR ANVARI, ZAHRA, & FAIZ, SEYYED HAMID REZA. (2011). USE OF REMIFENTANIL AND ALFENTANIL IN ENDOTRACHEAL INTUBATION: A COMPARATIVE STUDY. ANESTHESIOLOGY AND PAIN MEDICINE, 1(2 (2)), 61-65. SID. https://sid.ir/paper/328377/en

    Vancouver: Copy

    IMANI FARNAD, ALEBOUYEH MAHMOUD REZA, TAGHIPOUR ANVARI ZAHRA, FAIZ SEYYED HAMID REZA. USE OF REMIFENTANIL AND ALFENTANIL IN ENDOTRACHEAL INTUBATION: A COMPARATIVE STUDY. ANESTHESIOLOGY AND PAIN MEDICINE[Internet]. 2011;1(2 (2)):61-65. Available from: https://sid.ir/paper/328377/en

    IEEE: Copy

    FARNAD IMANI, MAHMOUD REZA ALEBOUYEH, ZAHRA TAGHIPOUR ANVARI, and SEYYED HAMID REZA FAIZ, “USE OF REMIFENTANIL AND ALFENTANIL IN ENDOTRACHEAL INTUBATION: A COMPARATIVE STUDY,” ANESTHESIOLOGY AND PAIN MEDICINE, vol. 1, no. 2 (2), pp. 61–65, 2011, [Online]. Available: https://sid.ir/paper/328377/en

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